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WHO warns nearly 500 confirmed Ebola cases in Central Africa outbreak
Nearly 500 Ebola cases have now been confirmed in the deadly outbreak raging in central Africa, a WHO overview showed on Saturday, amid mounting concern over the swelling scale of the epidemic. In its daily update on the situation, the World Health Organization tallied 452 confirmed cases, including 82 deaths, in the Democratic Republic of Congo (DR Congo), where the outbreak was declared three weeks ago. In neighbouring Uganda, meanwhile, it counted 19 confirmed cases, including two deaths.
Mitochondria directly interact with the nuclear pore complex
Abstract Mitochondria regulate cellular processes through direct and indirect interactions with other organelles. A well-studied example has been contact with the endoplasmic reticulum at mitochondrial-associated endoplasmic reticulum membranes1, which control pathways including redox and calcium homeostasis2,3. Recent studies have also reported direct mitochondria–nuclear membrane contacts in cancer cells and yeast that promote pro-survival signalling4,5.
Efficient and accurate neural-field reconstruction using resistive memory
Abstract Applications such as medical imaging, augmented and virtual reality, and embodied artificial intelligence (AI) depend on the ability to reconstruct complex signals from sparse observations. These applications are characterized by incomplete measurements and limited computational resources. Traditional approaches to digital hardware face the following challenges: explicit signal representations require heavy sampling and storage, data movement across the von Neumann bottleneck...
US doctor recovers from Ebola in Germany as DRC cases surge to 488
US doctor recovers from Ebola in Germany as DRC cases surge to 488 Berlin’s Charite hospital hailed treatment as a ‘significant therapeutic success’ as outbreak spreads in DR Congo. A doctor from the United States who fell ill with Ebola while working in the Democratic Republic of the Congo (DRC) has recovered after more than two weeks of treatment in Germany, according to the hospital that admitted him. The Charite public hospital in Berlin said the man – identified in media reports as...
Amplified Arctic iceberg traffic reshapes benthic biodiversity
Abstract The Arctic is undergoing rapid warming, resulting in retreating sea ice and glaciers1, yet how cryospheric changes propagate into the deep ocean remains poorly understood2. Here we identify a climate-driven mechanism linking accelerating glacier disintegration to an increase in deep-sea hard-bottom habitats far beyond calving fronts. Seafloor observations in Fram Strait show a localized increase in the density and patchiness of dropstones delivered by debris-laden icebergs.
A prognostic human brain network for diffuse midline glioma
Abstract Diffuse midline gliomas (DMGs) are near-universally lethal tumours of the childhood central nervous system1,2. In animal models, DMGs form brain-wide integrated networks through neuron-to-glioma synapses3,4,5,6 and glioma-to-glioma gap junctional coupling3. This extensive connectivity robustly promotes the growth and invasion of DMG3,4,5,6,7,8,9 and other glial malignancies10,11,12 through paracrine mechanisms and direct neuron-to-glioma synapses.
EU announces €5 million boost to Ebola response in DRC
As Ebola cases in the Democratic Republic of the Congo climb above 450 and fears grow of a wider regional outbreak, the European Union has announced an additional €5 million to strengthen testing and disease surveillance. The European Union has announced an additional €5 million in funding to support efforts to contain the latest Ebola outbreak in eastern Democratic Republic of the Congo, as European Commissioner for Crisis Management Hadja Lahbib visited the region on Sunday. Speaking after...