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Lignin to adipic acid in a high-yield chemical and biological redox process
Abstract Viable manufacturing pathways to produce bio-based chemicals from renewable feedstocks, such as lignin derived from plant biomass, are needed to decarbonize the chemicals manufacturing sector. Converting the recalcitrant lignin polymer to valuable bioproducts remains a longstanding challenge in biorefining, with the highest reported single-product yield from lignin currently around 20 wt% (refs. Most existing lignin depolymerization strategies target aryl–ether bond cleavage, which...
The Ringelmann Effect in Multi-Agent LLM Systems: A Scaling Law for Effective Team Size
arXiv:2606.02646v1 Announce Type: cross Abstract: Inference-time multi-agent LLM scaling lacks a shared unit: counting nominal agents conflates cost with independent evidence. We derive a two-parameter scaling law $R(N) = N_\text{eff}/N = 1/(1+c(N-1)N^{-\beta})$ where the regime exponent $\beta$ classifies any configuration into one of three asymptotic regimes -- hard-ceiling at $1/c$ ($\beta = 0$), sublinear at $N^\beta/c$ ($0 0.99$; only $(c, \beta)$ shifts. On free-form math, dense peer...
The Ringelmann Effect in Multi-Agent LLM Systems: A Scaling Law for Effective Team Size
arXiv:2606.02646v1 Announce Type: new Abstract: Inference-time multi-agent LLM scaling lacks a shared unit: counting nominal agents conflates cost with independent evidence. We derive a two-parameter scaling law $R(N) = N_\text{eff}/N = 1/(1+c(N-1)N^{-\beta})$ where the regime exponent $\beta$ classifies any configuration into one of three asymptotic regimes -- hard-ceiling at $1/c$ ($\beta = 0$), sublinear at $N^\beta/c$ ($0 0.99$; only $(c, \beta)$ shifts. On free-form math, dense peer...
Light-induced quantum friction of carbon nanotubes in water
Abstract Friction slows down moving objects at both macroscopic and microscopic scales1. At the electronic level, quantum friction describes direct transfer of momentum between a liquid and the electrons of a solid2. Owing to its microscopic nature, this phenomenon remains experimentally challenging to capture3.
Perfect divisibility and perfect-Pollyanna in bull-free graphs
arXiv:2603.21538v2 Announce Type: replace-cross Abstract: A graph $G$ is {\em perfectly divisible} if, for each induced subgraph $H$ of $G$, $V(H)$ can be partitioned into $A$ and $B$ such that $H[A]$ is perfect and $\omega(H[B])<\omega(H)$. A {\em bull} is a graph consisting of a triangle with two disjoint pendant edges. Ho\`ang [Discrete Math. 349 (2026) 114809] proposed four conjectures: 1.
SIRT7 regulates dosage compensation and safeguards the female X chromosome
Abstract Sirtuins are deacetylases implicated in stress responses and longevity in mammals1,2. Although their differential impact on disease for the two sexes has been noted3,4,5,6,7, the underlying reasons are unclear. Here, using Sirt7 as a model in mice, we examine the mechanisms leading to sex differences and find that Sirt7−/− female mice have decreased fitness throughout their lifespan.
Molecular glue degraders of HuR suppress BRAF-mutant colorectal cancer
Abstract BRAF gain-of-function mutations, particularly BRAF(V600E), affect roughly 10% of all patients with colorectal cancer (CRC), and portend poor prognosis with limited therapeutic interventions. BRAF inhibitors such as encorafenib are ineffective due to MAPK pathway reactivation driven by BRAF dimerization. Combined inhibition of BRAF and EGFR, although approved therapies, results in short survival benefits and frequent treatment resistance and relapse1,2,3.
The Last Evolution, by John W Campbell Jr. (1932)
The Project Gutenberg EBook of The Last Evolution, by John Wood Campbell This eBook is for the use of anyone anywhere at no cost and with almost no restrictions whatsoever. You may copy it, give it away or re-use it under the terms of the Project Gutenberg License included with this eBook or online at www.gutenberg.org
Amplified Arctic iceberg traffic reshapes benthic biodiversity
Abstract The Arctic is undergoing rapid warming, resulting in retreating sea ice and glaciers1, yet how cryospheric changes propagate into the deep ocean remains poorly understood2. Here we identify a climate-driven mechanism linking accelerating glacier disintegration to an increase in deep-sea hard-bottom habitats far beyond calving fronts. Seafloor observations in Fram Strait show a localized increase in the density and patchiness of dropstones delivered by debris-laden icebergs.
Two-component exciton condensates in an electron–hole bilayer
Abstract Macroscopic quantum coherence emerges when bosons condense into a Bose–Einstein condensate (BEC)1,2,3,4,5. Excitons are a long-sought solid-state route to high-temperature BECs with strong interactions, electrical tunability and potentially multicomponent spinor order, but conclusive evidence for equilibrium condensation has remained elusive. Here we report evidence for two-component exciton BECs in MoSe2/hBN/WSe2 electron–hole bilayers6,7,8,9 by probing the spin–valley...