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Accurate Small-Signal Modeling of Digitally Controlled Buck Converters with ADC-PWM Synchronization

Announce Type: replace Abstract: Digital control has become increasingly widespread in modern power electronic converters. When acquiring feedback signals such as the inductor current, synchronizing the analog-to-digital converter (ADC) with the digital pulse-width modulator (DPWM) is commonly employed to accurately track their steady-state average. However, the small-signal implications of such synchronization have not been investigated.

arXiv CS 8d ago

Rapid Determination of Drug-to-Antibody Ratios in Antibody Drug Conjugates Using Ultrafast Microdroplet Digestion Technology

Accurate determination of drug to antibody ratios (DARs) is essential for the development, quality control, and performance evaluation of antibody drug conjugates (ADCs); yet conventional analytical approaches often require extensive sample preparation, long analysis time, and substantial sample consumption. The peak distribution of intact ADCs is highly complex due to inherent glycosylation heterogeneity and variable drug conjugation. By applying enzymatic digestion, ADC can be converted...

bioRxiv 5d ago

An Algebraic-Diagrammatic Construction for Vertex Corrections to the $GW$ Self-Energy

new Abstract: The $G3W2$ approximation -- the second-order self-energy beyond $GW$ -- is known to violate some fundamental analytic properties of the self-energy. In particular, its lack of positive semi-definiteness leads to unphysical features such as negative spectral functions. In this work, we reformulate the $G3W2$ approximation within the algebraic-diagrammatic construction (ADC) framework.

arXiv Physics 6d ago

NeuDW-CIM: a 65-nm 0.8-pJ/Sop Reconfigurable Neuromorphic Compute-in-Memory Macro with Nonlinear Dendrites and K-Winners

arXiv:2606.08947v1 Announce Type: new Abstract: This work presents NeuDW-CIM, a highly efficient neuromorphic Compute-in-Memory (CIM) macro for Spiking Neural Networks (SNNs) implemented in 65 nm CMOS. The design introduces a custom twin 9T bit-cell for ternary in-puts/weights and a reconfigurable non-linear In-Memory ADC (IMA).

arXiv CS 1d ago

Stability Analysis for Autoregressive Sampling Sets

Announce Type: cross Abstract: Motivated by recent developments in stochastic modeling of clock jitter in Analog-to-Digital Converters (ADCs) as autoregressive processes of order one (AR(1)), we study the density and stability properties of AR(1)-jittered sampling sets for Paley-Wiener signals. We show that, despite having the correct asymptotic density both on average and almost surely, such sets almost surely fail to be stable sampling sets. We complement this negative result with a...

arXiv CS 7d ago

A Reconfigurable Computing In-Memory Macro with Charge-sharing-based Weighted Accumulator

Announce Type: new Abstract: SRAM-based analog computing-in-memory demonstrates outstanding efficiency. However, it faces three critical challenges: significant ADC overhead, high latency for multi-bit inputs, and limited read bitline voltage. To address these issues, this work proposes a multi-bit highly reconfigurable 256x128 in-memory computing array supporting 1-7b input, 2-4b weight, and 1-7b output.

arXiv CS 9d ago

Investigating Energy Bounds of Analog Compute-in-Memory with Local Normalization

arXiv:2602.08081v2 Announce Type: replace Abstract: Modern edge AI workloads demand maximum energy efficiency, motivating the pursuit of analog Compute-in-Memory (CIM) architectures. Simultaneously, the popularity of Large-Language-Models (LLMs) drives the adoption of low-bit floating-point formats which prioritize dynamic range. However, the conventional direct-accumulation CIM accommodates floating-points by normalizing them to a shared widened fixed-point scale.

arXiv CS 1d ago

Queen Elizabeth’s mother wanted her to marry another man before Prince Philip: author

Before Prince Philip captured Queen Elizabeth II's heart, another aristocratic suitor may have been in the running for the future monarch. According to royal historian Hugo Vickers, author of "Queen Elizabeth II: A Personal History," his research revealed that Hugh, Earl of Euston — who later became the 11th Duke of Grafton — was considered a potential match for the young princess before she ultimately fell for the man who would become the love of her life. "The Queen Mother was very keen...

Fox News 9d ago

UK's GSK to acquire U.S. drugmaker Nuvalent for $10.6 billion as pharma giants race to expand pipelines

U.K. pharmaceutical group GSK has entered an agreement to acquire U.S.-based drugmaker Nuvalent for $10.6 billion to bolster its lung cancer pipeline, in what would be the British drugmaker's largest acquisition in more than a decade. The all-cash deal values Nuvalent at about $124 per share, according to a GSK filing on Tuesday, representing a 40% premium to its last closing price. The Financial Times had reported the transaction earlier on Tuesday.

CNBC 1d ago