ASD
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Related Articles from SNS
The ASD Risk Gene D5Ertd579e Regulates Synaptic Plasticity and Selective Autism-Related Behaviors
Autism spectrum disorder (ASD) is a heterogeneous neurodevelopmental condition shaped by contributions from hundreds of genes, many of which remain poorly characterized. This largely uncharacterized genomic landscape may therefore hold critical insight into how diverse molecular disruptions converge on shared social phenotypes. Here, we investigated KIAA0232 (mouse orthologue D5Ertd579e), an uncharacterized locus lacking known functional domains, using a global null knockout mouse model.
Analysis of Ethnic Disparities in Autism Spectrum Disorder among Toddlers
arXiv:2606.01217v1 Announce Type: new Abstract: Autism Spectrum Disorder (ASD) is a neurodevelopmental disorder characterized by challenges in communication and behavior. This study examines the relationship between ethnicity and ASD traits, along with behavioural scores, sex and neonatal jaundice across three ethnic groups: White Europeans, Asians, and Middle Eastern individuals. We perform a logistic regression and show that ethnicity has a significant effect on incidence of ASD.
3D Temporal Analysis for Autism Spectrum Disorder Screening During Attention Tasks
arXiv:2606.04836v1 Announce Type: new Abstract: Accurate Autism Spectrum Disorder (ASD) screening for school-age children is crucial to identify cases that may have been missed earlier and to enable timely interventions supporting social, cognitive, and academic development. Current ASD screening relies on subjective assessments and 2D analysis methods that fail to capture spatial displacement patterns characteristic of ASD behaviors. In this study, a novel 3D temporal analysis framework is...
An ERP Study on Recursive Locative Processing in Mandarin-Speaking Children with Autism
arXiv:2606.05620v1 Announce Type: new Abstract: Recursion enables the generation of hierarchical linguistic structures but imposes substantial processing demands during real-time comprehension. While difficulties with complex syntax have been reported in autism spectrum disorder (ASD), the temporal dynamics of recursive processing remain poorly understood. This study used event-related potentials (ERPs) to examine how Mandarin-speaking children with ASD process two-level recursive locative...
Fetal MRI reveals altered prenatal cortical surface area in fetuses later diagnosed with autism spectrum disorder
Autism spectrum disorder (ASD) is increasingly conceptualized as a condition rooted in altered prenatal neurodevelopment, yet in vivo evidence from fetal brain imaging remains limited. Using retrospective fetal MRI and surface-based morphometry, we investigated cortical development in 15 fetuses later diagnosed with ASD (77%; mean gestational age [GA] = 26.7 weeks) without major structural brain abnormalities and compared them with 60 typically developing controls (57% male; mean GA = 28.4...
Dimensional Arousal and Categorical Gaze Instability: Uncoupling the Baseline Oculomotor Phenotypes of Autism and ADHD
Background: Autism Spectrum Disorder (ASD) and Attention-Deficit/Hyperactivity Disorder (ADHD) share substantial clinical and physiological overlap. While naturalistic and sensory-driven paradigms increasingly capture evoked neurophysiological responses, the intrinsic baseline physiology of these conditions remains poorly defined. We aimed to characterize resting-state autonomic arousal and oculomotor stability across the ASD-ADHD spectrum using both continuous (RDoC) and categorical (DSM-5)...
Social Novelty Recruits a Dysfunctional Nucleus Accumbens Ensemble That Drives Social Avoidance in a Shank3-/- Autism Model
Social behavior deficits are a common symptom of neuropsychiatric disorders, including autism spectrum disorder (ASD), but there are limited pharmacological treatments for these symptoms. Understanding how neurons encode social information will give insight into identifying novel pharmacological targets to address this unmet need. SHANK3 encodes a postsynaptic scaffold protein and is a common risk gene for several neuropsychiatric disorders characterized by social deficits, including ASD.
Asymmetric neural dynamics of visuospatial attention in autism spectrum disorder
Background: Selective attention enables the prioritization of behaviorally relevant information in complex sensory environments. Despite substantial evidence for altered attention in autism spectrum disorder (ASD), the neurophysiological mechanisms underlying these differences remain poorly understood. Here, we integrate high-density electroencephalography (EEG), pupillometry, and behavioral measures collected during a cued covert visuospatial selective attention task to characterize...
The Taiz transplant team looking to begin a medical revolution in Yemen
The Taiz transplant team looking to begin a medical revolution in Yemen Taiz’s Cardiac and Vascular Diseases and Kidney Transplant Center has provided hundreds of Yemenis with affordable and lifesaving treatment. A young girl lies in a hospital bed in Taiz, southwest Yemen, recovering from surgery to treat her atrial septal defect (ASD), better known as “hole in the heart”. “May I take a picture of you?”
Attenuated adaptive growth of interpersonal synchrony in autism
During social interactions, people continuously align their movements and rhythms, a process known as interpersonal synchrony that supports rapport, mutual understanding, and smooth communication. In autism spectrum disorder (ASD), previous studies have often reported atypical or reduced synchrony, but most have relied on aggregate or session-averaged measures that may miss how coordination develops over time. It therefore remains unclear whether interactional differences in autism reflect a...