Beacon
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The Happy Pod: The surprise star of a US Olympics team
With the Paris Olympics underway, we hear about Beacon -- the therapy dog that's helped the USA Gymnastics team cope with the pressure and stress of competitive sport. His handler and owner, Tracey, tells us his friendly face and intuitive nature make him perfect for the job -- and that some of the gymnasts even talk to him. Also: the first horse rider from the Arab world to qualify for Olympic equestrian eventing tells us it's a huge honour to represent the region's history.
Mountain rescue's 12-hour operation to clear 'river of rubbish' seen 3 miles away
Central Beacons Mountain Rescue Team said they removed over a tonne of waste from the beauty spot.
Mountain rescue's 12-hour operation to clear 'river of rubbish' seen 3 miles away
Central Beacons Mountain Rescue Team said they removed over a tonne of waste from the beauty spot.
Mountain rescue's 12-hour operation to clear 'river of rubbish' seen 3 miles away
Central Beacons Mountain Rescue Team said they removed over a tonne of waste from the beauty spot.
The station that shamed New York is finally getting an $8bn makeover
The station that shamed New York is finally getting an $8bn makeover Renderings of a dramatically redesigned Pennsylvania Station in New York City have been released by Amtrak and the developers it has selected for the estimated $8 billion project - Bookmark A dramatic new vision has been unveiled for Manhattan's Penn Station, promising to transform the notoriously gloomy transit hub back into a beacon of architectural grandeur, reminiscent of its original, majestic form. The station, once a...
Giant crowds greet Pope Leo at public mass in Madrid, Spain
Giant crowds greet Pope Leo at public mass in Madrid, Spain The pontiff praises Madrid as a beacon of inclusion as about 1.2 million people gather for Sunday mass. An oceanic crowd has filled the streets of the Spanish capital Madrid with chants, cheers and applause to greet Pope Leo XIV on the second day of a weeklong apostolic journey to mainland Spain and the Canary Islands.
Mountain rescue's 12-hour operation to clear 'river of rubbish' seen 3 miles away
Central Beacons Mountain Rescue Team said they removed over a tonne of waste from the beauty spot.
Rescue team's 12-hour operation to clear 'river of rubbish' from mountain beauty spot
Central Beacons Mountain Rescue Team said they removed over a tonne of waste from the beauty spot.
Platner’s ‘living on the sea’ claim dismantled by critics as financial docs paint a different picture
Democratic Senate candidate Graham Platner claimed that he has been able to "make a living on the sea" since leaving the armed forces during a Friday rally, an assertion his financial disclosures don’t appear to support. Platner, who is running for Senate in Maine to unseat incumbent GOP Sen. Susan Collins, has long identified himself as an oyster farmer and harbor master, giving a blue-collar tinge to his left-wing campaign. Financial disclosures, however, show that he brings in relatively...
Molecular glue degraders of HuR suppress BRAF-mutant colorectal cancer
Abstract BRAF gain-of-function mutations, particularly BRAF(V600E), affect roughly 10% of all patients with colorectal cancer (CRC), and portend poor prognosis with limited therapeutic interventions. BRAF inhibitors such as encorafenib are ineffective due to MAPK pathway reactivation driven by BRAF dimerization. Combined inhibition of BRAF and EGFR, although approved therapies, results in short survival benefits and frequent treatment resistance and relapse1,2,3.