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DXA-Derived Skeletal Phenotypes and Hip Fracture Risk: A Backdoor-Adjusted Causal Analysis

Announce Type: cross Abstract: Purpose: To compare dual-energy X-ray absorptiometry (DXA)-derived hip skeletal phenotypes in relation to hip fracture risk using prespecified confounder adjustment and to assess whether phenotypes ranked by their backdoor-adjusted average treatment effects (ATEs) improve risk stratification. Methods: We analyzed 21,098 UK Biobank participants with linked health records, hip DXA-derived skeletal measures, and prespecified covariates. Sixteen phenotypes spanning...

arXiv CS 7d ago

Towards a holistic understanding of Selection Bias for Causal Effect Identification

Announce Type: replace-cross Abstract: Selection bias is pervasive in observational studies. For example, large scale biobanks data can exhibit ``healthy volunteer bias'' when respondents are healthier and of higher socio-economic status than the population they are meant to represent. Recovering causal effects from such sub-population is an important problem in causal inference, as estimating average treatment effects (ATE) from selected populations can result in a severely biased estimate...

arXiv CS 8d ago

Towards a holistic understanding of Selection Bias for Causal Effect Identification

arXiv:2605.13430v2 Announce Type: replace-cross Abstract: Selection bias is pervasive in observational studies. For example, large scale biobanks data can exhibit ``healthy volunteer bias'' when respondents are healthier and of higher socio-economic status than the population they are meant to represent. Recovering causal effects from such sub-population is an important problem in causal inference, as estimating average treatment effects (ATE) from selected populations can result in a...

arXiv CS 9d ago

Chain of Flow: ECG-Conditioned 4D Cardiac Cine Generation from Patient-Specific Anatomical Anchor

Announce Type: replace Abstract: Cardiac cine magnetic resonance imaging (MRI) is central to functional cardiac assessment, yet a full current cine sequence may not always be directly available at the point of analysis. We introduce Chain of Flow (COF), an electrocardiography (ECG)-conditioned framework that combines patient-specific MRI and current ECG for subject-specific 4D cardiac cine generation. On the UK Biobank dataset, COF achieves strong image-level fidelity and downstream...

arXiv CS 1d ago

Autonomous AI screening flags unreliable Lyme test results, boosting sensitivity to 95.7%

Autonomous AI screening flags unreliable Lyme test results, boosting sensitivity to 95.7% Andrew Zinin Lead Editor Computational point-of-care sensors can significantly improve access to diagnostics by enabling rapid patient testing outside centralized medical facilities. These tests rely on machine learning models to make diagnostic predictions, but such inference models are susceptible to hallucinations and may produce erroneous outcomes. As a result, their limited reliability has...

Phys.org 3d ago

Disentangling Latent Risk Pathways via Bayesian Hypergraph Inference

Announce Type: cross Abstract: Electronic health records (EHR) pose large-scale multi-disease modeling problems in which many outcomes are rare and strongly influenced by shared risk factors. While modern approaches achieve strong predictive performance, they often treat diseases independently or rely on black-box architectures, offering limited insight into how risk factors organize disease risk and little principled uncertainty quantification. We introduce a Bayesian hypergraph inference...

arXiv CS 1d ago

CardioMorphNet: Cardiac Motion Prediction Using a Shape-Guided Bayesian Recurrent Deep Network

Announce Type: replace Abstract: Accurate cardiac motion estimation from cine cardiac magnetic resonance (CMR) images is vital for assessing cardiac function and detecting its abnormalities. Existing methods often struggle to accurately capture heart motion because they rely on intensity-based image registration similarity losses that may overlook cardiac anatomical regions. To address this, we propose CardioMorphNet, a recurrent Bayesian deep learning framework for 3D cardiac shape-guided...

arXiv CS 1d ago

Gradient-Flow Optimization as Dynamic Random-Effects Inference: Testing and Early Stopping with Applications to Deep Learning

arXiv:2605.27991v2 Announce Type: replace-cross Abstract: Gradient-flow optimization is usually viewed as an algorithmic procedure for minimizing empirical loss, with training duration selected by validation or heuristic early-stopping rules. We develop a statistical inference framework for the gradient-flow training trajectory itself. The central object is fixed-operator squared-error gradient flow: whenever the fitted value evolves through a time-invariant positive semidefinite training...

arXiv CS 5d ago