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FlcE latches onto the FliL-stator complex to turbocharge flagellar motility in Borrelia burgdorferi

Periplasmic flagella are essential for the distinctive morphology and motility of the Lyme disease spirochete Borrelia burgdorferi, and motility plays a critical role in its pathogenic lifestyle. These flagella are powered by specialized motors that contain a large spirochete-specific multiprotein collar complex, yet the molecular architecture and mechanisms underlying high-torque motility remain poorly understood. Here, we identify the tetratricopeptide repeat (TPR)-containing protein...

bioRxiv 11d ago

Rare type of Lyme disease found for the first time in New York

There’s a new type of Lyme disease in New York state. Almost all cases of the tick-borne illness in the United States are caused by corkscrew-shaped bacteria called Borrelia burgdorferi. But B. burgdorferi is actually one of two Lyme disease-causing species in the U.S.

NBC News 6d ago