Cardiac
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CardioMorphNet: Cardiac Motion Prediction Using a Shape-Guided Bayesian Recurrent Deep Network
Announce Type: replace Abstract: Accurate cardiac motion estimation from cine cardiac magnetic resonance (CMR) images is vital for assessing cardiac function and detecting its abnormalities. Existing methods often struggle to accurately capture heart motion because they rely on intensity-based image registration similarity losses that may overlook cardiac anatomical regions. To address this, we propose CardioMorphNet, a recurrent Bayesian deep learning framework for 3D cardiac shape-guided...
Chain of Flow: ECG-Conditioned 4D Cardiac Cine Generation from Patient-Specific Anatomical Anchor
Announce Type: replace Abstract: Cardiac cine magnetic resonance imaging (MRI) is central to functional cardiac assessment, yet a full current cine sequence may not always be directly available at the point of analysis. We introduce Chain of Flow (COF), an electrocardiography (ECG)-conditioned framework that combines patient-specific MRI and current ECG for subject-specific 4D cardiac cine generation. On the UK Biobank dataset, COF achieves strong image-level fidelity and downstream...
The hypertrophic cardiomyopathy mutation G768R makes cardiac myosin a high duty ratio motor
{beta}-cardiac myosin is the primary motor protein in the human heart responsible for force generation by converting chemical energy from ATP hydrolysis to mechanical work. It binds actin, produces force through its powerstroke, and releases actin, and must complete this cycle several times a second within each heartbeat. Like other muscle myosins, cardiac myosin has a low duty ratio of ~5%, the fraction of time in the actin-bound force-producing state.
Learning Cardiac Latent Representations in Vectorcardiogram Space
arXiv:2605.31249v1 Announce Type: new Abstract: Electrocardiography (ECG) is a cornerstone of cardiac assessment, making the learning of informative ECG representations fundamental to tasks ranging from disease diagnosis to clinical report generation. However, existing methods operate almost exclusively in the observable ECG signal space. In practice, the standard twelve-lead ECG represents multiple projections of the same underlying cardiac electrical activity from different spatial...
Primary cilia promote cardiac fibrosis and limit heart function after myocardial infarction
Cardiomyocytes die and do not regenerate after an injury such as a myocardial infarction (MI), a leading cause of mortality worldwide. Following MI, cardiac fibroblasts (CFs) proliferate and differentiate into myofibroblasts, which then produce increased collagen and extracellular matrix (ECM) leading to fibrosis. Fibrosis can weaken cardiac output via excessive stiffening and interference with electric signal transmission, but can also prevent wall rupture under load.
Fitness at what cost? Cardiac emergencies, fatal mishaps put gym safety in spotlight
With the increase in the popularity of gymnasiums and fitness regimes in India, there have been a number of unfortunate incidents reported, which range from cardiac arrests at the gym to accidents and fights within fitness centers. There have been many instances where people have died due to heart attacks and accidents while working out in the gym. One of the most widely discussed cases was the death of comedian and actor Raju Srivastava in September 2022.
NFL star says cardiac arrest was ‘not even top three’ hardest moments
Buffalo Bills safety Damar Hamlin nearly died on national television in January 2023. Three years later, he made a statement that hits harder than the collapse itself. In an as-told-to essay with Business Insider’s Kelly Burch, Hamlin said going into cardiac arrest during an NFL game was not the toughest thing he has survived.
Doctors say Trump’s medical report ‘lacks crucial information about his cardiac health’
Doctors say Trump’s medical report ‘lacks crucial information about his cardiac health’ Doctors said the medical record lacked details regarding the health of his heart, including how much blood it’s pumping, according to a report - Bookmark - CommentsGo to comments A White House report describing Donald Trump’s recent medical examination lacks crucial information around the results of his cardiovascular testing, physicians who read the memorandum have told the Wall Street Journal. Trump...
Hypertension-mediated cardiac fibrosis is a mechanical process initiated by smooth muscle cells
Hypertension represents the most prevalent chronic cardiovascular condition, typically culminating in pathological cardiac remodeling characterized by hypertrophy and extensive fibrosis. Although the cellular phenotypes associated with these changes are well-documented, the precise mechanisms by which hypertensive stress is sensed and transduced into a fibrotic program remain poorly defined. To elucidate these mechanisms, we investigated the role of Lysyl oxidase (LOX), an extracellular...
Motion-Guided Causal Disentanglement for Robust Multi-View Cine Cardiac MRI Diagnosis
Announce Type: new Abstract: Multi-view cardiac magnetic resonance (CMR) imaging provides complementary anatomical information and is widely used for noninvasive disease assessment. Recent transformer-based models have demonstrated strong representation learning capabilities for CMR analysis; however, they typically learn unified latent embeddings that entangle view-specific anatomical variations with disease-related features. Such entanglement biases classifiers toward structural attributes...