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Extracellular vesicles from Manila clam (Ruditapes philippinarum): tailored isolation from hemolymph and insights into water-derived vesicles
Extracellular vesicles (EVs) are evolutionarily conserved mediators of intercellular communication released by cells into biological fluids and the extracellular environment. Despite their growing relevance in biomedical and veterinary research, knowledge on EVs in marine bivalves remains limited. The aim of this study was to optimize tailored protocols for EV isolation from the hemolymph of the Manila clam (Ruditapes philippinarum) based on density gradient ultracentrifugation (dgUC) or...
Bees can swim and use visual cues to survive water crashes
Bees can swim and use visual cues to survive water crashes Gaby Clark Scientific Editor Robert Egan Associate Editor When a bee crashes into water, it may still be able to swim to safety. New research from Michigan State University confirms that honeybees can propel themselves across the water's surface, and their movement is purposeful and directional. They swim toward darker areas—likely using visual cues to locate the shoreline and escape.
Brain scans reveal two distinct types of autism
Brain scans reveal two distinct types of autism Scientists have revealed two hidden brain-based forms of autism, a breakthrough that could help tailor future treatments to each person's biology. - Date: - June 3, 2026 - Source: - Istituto Italiano di Tecnologia - IIT - Summary: - Scientists have uncovered evidence that autism may include at least two biologically distinct subtypes, each marked by a different pattern of brain communication.
Where did language come from? Nobody really knows, but the theories are fascinating
Where did language come from? Nobody really knows, but the theories are fascinating Lisa Lock Scientific Editor Andrew Zinin Lead Editor Humans are the only species known to use fully symbolic language: a system capable of expressing abstract ideas, imaginary worlds and endless combinations of meaning. But how did we get there?
Hardy ice plant's optical innovation inspires reflective design possibilities
Nature is filled with remarkable visual phenomena created by microscopic surface structures that interact with light in fascinating ways. The iridescent wings of butterflies, the shimmering feathers of birds and the glossy surfaces of flower petals are all examples of how living organisms control the reflection, absorption and scattering of light. These optical effects are not only visually striking but also serve important biological functions, including attracting pollinators,...
The secret to pigeons’ incredible navigation was hiding in their liver
The secret to pigeons’ incredible navigation was hiding in their liver Pigeons may owe their remarkable homing ability not to their brains or eyes, but to magnetic-sensing immune cells hidden in their livers. - Date: - May 31, 2026 - Source: - Max Planck Institute of Animal Behavior - Summary: - Scientists have uncovered a surprising navigation system in pigeons: iron-filled immune cells in the liver that may act like tiny magnetic sensors. Birds deprived of these cells struggled to find...
PAG-Agent: a biologist-oriented research assistant for context-aware pathway-level analysis and interpretation
Pathway analysis is a critical step for translating gene-level omics results into biological mechanisms, yet existing workflows often leave researchers with long lists of statistically significant pathways that are difficult to interpret, validate, and connect to experimental context. We developed PAG-Agent, a biologist-oriented virtual research assistant that integrates pathway-level statistical analysis, context-aware biological interpretation, literature-supported reasoning, and...
Convergent Evolution in Tumor Genomes Targets Functional Domains
Tumor evolution is shaped by selective pressures that repeatedly favor similar functional outcomes across genetically distinct cancers. While convergent evolution in cancer has been studied at the gene level, this work investigates selection on smaller functional units, namely protein domains. Using >9,500 primary tumor exomes from The Cancer Genome Atlas, we quantified selection strengths acting on missense and truncating mutations aggregated by protein domain.
Living brain gene activity revealed noninvasively through programmable blood test
Living brain gene activity revealed noninvasively through programmable blood test Stephanie Baum Scientific Editor Robert Egan Associate Editor Cell function is determined by how DNA is expressed into proteins. That process includes two main steps—transcription, when messenger RNA (mRNA) makes copies of active genes; and translation, when mRNA guides protein assembly. Knowing which genes are active at any given moment would make it possible to track the body's response to factors in the...
SSRI antidepressants are often 'carelessly prescribed'
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