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Related Articles from SNS

One Loss to Rule Them All: Marked Time-to-Event for Structured EHR Foundation Models

Announce Type: replace Abstract: Clinical events captured in Electronic Health Records (EHR) are irregularly sampled and may consist of a mixture of discrete events and numerical measurements, such as laboratory values or treatment dosages. The sequential nature of EHR, analogous to natural language, has motivated the use of next-token prediction to train prior EHR Foundation Models (FMs) over events. However, this training fails to capture the full structure of EHR.

arXiv CS 2d ago

Beyond Prediction: Longitudinal Reasoning in EHR-Integrated Clinical AI

arXiv:2606.08413v1 Announce Type: new Abstract: We present a structured analysis of how contemporary clinical AI systems integrate electronic health record (EHR) data and the extent to which they support longitudinal clinical reasoning. Drawing on a curated corpus of clinical natural language processing (NLP) and EHR-integrated systems, we develop a coding framework that captures both technical integration strategies and reasoning-relevant representational features, such as trajectory...

arXiv CS 1d ago

Accelerating Reproducible Research in Synthetic EHR Generation

Announce Type: new Abstract: The generation of high-fidelity synthetic Electronic Health Records (EHR) is crucial for advancing medical research while preserving patient privacy. However, head-to-head comparison of existing generative models is hindered by disjointed codebases, incompatible data loaders, conflicting library dependencies, and inconsistent evaluation protocols. To address these gaps, we introduce a lightweight, end-to-end benchmarking framework for reproducible synthetic EHR...

arXiv CS 2d ago

EHRBench: An Automated and Reliable EHR-based Benchmark for Clinical Decision Making with LLMs

arXiv:2605.30637v1 Announce Type: new Abstract: Clinical decision-making (CDM) is central to real-world clinical workflows, where clinicians infer diagnoses, select treatments, or anticipate future health outcomes under incomplete evidence. LLMs are increasingly used to support these decisions due to strong language capabilities, broad biomedical knowledge, and efficiency, yet the reliability of LLMs on real-world clinical decision tasks remains insufficiently understood. To evaluate CDM...

arXiv CS 9d ago

ClinEnv: An Interactive Multi-Stage Long Horizon EHR Environment for Agents

Announce Type: new Abstract: Clinical practice is not the selection of an answer from enumerated options: a physician gathers heterogeneous information incrementally and commits to sequential, irreversible decisions under uncertainty. Static benchmarks cannot probe and existing interactive medical benchmarks each compromise on at least one of them. We present ClinEnv, an interactive benchmark that evaluates LLMs as attending physicians over real inpatient admissions under a paradigm we term...

arXiv CS 8d ago

Curation of a Cardiology Interface Terminology for Highlighting Electronic Health Records using Machine Learning

Announce Type: new Abstract: Electronic health record (EHR) notes are dense medical documents containing large amounts of information, often filled with complex medical jargon. Highlighting all details in EHRs helps reduce the likelihood of missing crucial information by drawing attention to key content. This study proposes the design of a Cardiology Interface Terminology (CIT) to accurately highlight all details in EHR notes of cardiology patients.

arXiv CS 1d ago

ChatHealthAI: Aligning Electronic Health Record Representations with Large Language Models for Grounded Clinical Reasoning

arXiv:2606.02802v1 Announce Type: new Abstract: Large language models (LLMs) exhibit strong natural-language reasoning abilities for clinical decision support, but struggle to effectively model structured longitudinal electronic health records (EHRs). In contrast, EHR foundation models can learn predictive patient representations, yet lack interpretable language-based reasoning. To bridge this gap, we propose ChatHealthAI, a multimodal reasoning framework that aligns structured EHR...

arXiv CS 7d ago

ChatHealthAI: Aligning Electronic Health Record Representations with Large Language Models for Grounded Clinical Reasoning

arXiv:2606.02802v2 Announce Type: replace Abstract: Large language models (LLMs) exhibit strong natural-language reasoning abilities for clinical decision support, but struggle to effectively model structured longitudinal electronic health records (EHRs). In contrast, EHR foundation models can learn predictive patient representations, yet lack interpretable language-based reasoning. To bridge this gap, we propose ChatHealthAI, a multimodal reasoning framework that aligns structured EHR...

arXiv CS 1d ago

D2MDT: Department-aware Multidisciplinary Team Consultation with Deliberation for Efficient Clinical Prediction

arXiv:2606.03543v1 Announce Type: new Abstract: Electronic health records (EHRs) are central to clinical prediction, but existing methods either rely on correlation-driven deep models or use single large language models (LLMs), making it difficult to support multidisciplinary clinical reasoning. Recent multi-agent systems (MAS) provide a promising alternative, yet current EHR-grounded MAS methods still suffer from weak evidence differentiation across agents and redundant multi-round...

arXiv CS 7d ago

Early Prediction of Liver Cirrhosis Up to Two Years in Advance: A Machine Learning Study Benchmarking Against the FIB-4 and APRI Scores

Announce Type: replace Abstract: Objective: Develop and evaluate machine learning (ML) models for predicting incident liver cirrhosis (LC) one and two years prior to diagnosis using routinely collected electronic health record (EHR) data and benchmark their performance against the FIB-4 and APRI clinical scores. Methods: We conducted a retrospective cohort study using de-identified EHR data from a large academic health system. XGBoost models were developed for 1- and 2-year prediction...

arXiv CS 8d ago