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Related Articles from SNS
Genome Organizer SATB1 selectively activates a defined subset of EMT genes driving metastatic breast cancer
SATB1 reshapes chromatin architecture and transcriptional programs to promote breast cancer metastasis. However, its key downstream effectors remain incompletely defined. Here, we aimed to identify actionable drivers of invasion by focusing on epithelial-mesenchymal transition (EMT) genes.
Electromagnetic Navigation for Femoral Osteotomy Using High-Accuracy X-ray-to-CT Registration
arXiv:2606.03893v1 Announce Type: new Abstract: Accurate execution of preoperative plans in corrective femoral osteotomies remains challenging. Current techniques are limited by variable accuracy, invasiveness, and radiation exposure, with free-hand methods and patient-specific instrumentation (PSI) often requiring >30 and >6 fluoroscopic images, respectively. We present an integrated, electromagnetic tracking (EMT)-based navigation system for femoral osteotomies that minimizes dissection...
When Can Phasor-Domain Device Models Be Trusted for Electromechanical Stability Analysis of Grid-Forming Converter-Dominated Microgrids?
arXiv:2606.08082v1 Announce Type: new Abstract: Grid-forming (GFM) converter-dominated microgrids are often analyzed using reduced-order phasor-domain electromechanical GFM models, but the validity of these models is often taken for granted. Assuming ideal inner-loop tracking (IILT) of terminal-voltage references, these models neglect the inner-loop and filter dynamics at the electromagnetic-transient (EMT) timescale to simplify stability analysis. This paper argues that such neglected...
Systematic Gray-Box Identification Methodology for Voltage Source Converters
arXiv:2606.03567v1 Announce Type: new Abstract: This paper introduces a systematic gray-box identification framework for voltage-source converter models based solely on terminal time-series data. The proposed approach combines a physically informed white-box standard model with iterative time-domain calibration to estimate controller parameters that mimic the behavior of the black-box model in electromagnetic transient (EMT) simulations. Unlike conventional frequency-domain identification...
Loss of the Y chromosome drives epigenetic and transcriptomic plasticity in lung adenocarcinoma
Loss of the Y chromosome (LOY) is associated with poor survival across multiple solid tumors, yet the underlying molecular mechanisms remain poorly understood. Here, we identify LOY as a central driver of lineage plasticity and epigenetic heterogeneity in lung adenocarcinoma. Integrating multi-omic profiling of primary samples with isogenic cellular models, we show that LOY triggers epithelial-to-mesenchymal transition (EMT).
Loss of tissue specificity and recurrent pan-cancer activation define a conserved oncogenic microRNA class
MicroRNAs (miRNAs) act as crucial post-transcriptional regulators of large gene networks, and their aberrant expression drives key oncogenic processes such as epithelial-mesenchymal transition (EMT), angiogenesis, immune evasion, and metastasis. Oncogenic miRNAs that lose tissue specificity during malignant transformation represent promising therapeutic targets, as their restricted expression in healthy organs could minimize off-target effects. To identify these candidates, this study...
Enhancing Offshore Wind Simulations: Interpolated Switching via DLL Black-Boxes
Announce Type: new Abstract: The modern power system, increasingly composed of Inverter-Based Resources (IBR) from multiple manufacturers, requires new study and design techniques that balance accuracy with the need to protect the Intellectual Property (IP) of various stakeholders. One possible method to support detailed electromagnetic transient (EMT) simulations is to convert the original equipment manufacturers (OEM) models into shareable black-box versions using dynamic link libraries...
Small-Signal Analyses Using Analytical IBR Models and Frequency-Dependent Th\'evenin Equivalents
arXiv:2606.04538v1 Announce Type: new Abstract: This paper investigates whether component-level studies can capture additional interactions through Small Signal Analysis (SSA) when the network connected to the Voltage Source Converter (VSC), typically modeled as a simple Thevenin Equivalent, is a more complex IBR-based network. The research investigates cases ranging from basic analytical to an IEEE 9-Bus EMT model, with and without Inverter-Based Resources (IBRs), synthesized as State-Space...
Estimation of Equivalent SCR for Offshore Wind
arXiv:2606.03538v1 Announce Type: new Abstract: The integration of offshore wind power plants (OW-PPs) into weak grids can pose stability challenges due to the interaction between inverter-based resources (IBRs), Flexible AC Transmission Systems (FACTS) and the grid. In this context, long HVAC transmission systems, relatively common for OWPPs, can exacerbate the stability challenges. Therefore, this paper introduces a novel methodology for estimating the equivalent short-circuit ratio (ESCR)...
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