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Genomic connectivity and the spread of adaptive insecticide resistance alleles in Anopheles arabiensis from East Africa
Population connectivity and adaptive gene flow in disease vectors can shape the emergence and spread of insecticide resistance, with direct implications for control strategies such as insecticide spraying or the use of bed nets for malaria control. Using whole-genome sequencing, we first resolved the geographic population structure of the major but understudied malaria vector, Anopheles arabiensis, across the East African region, including the geographically diverse country of Ethiopia. We...
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