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Eupneic

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A noradrenergic Ih-dependent pacemaker system drives sniffing

Sniffs are rapid breaths generated to clear nasal passages, actively sample air for smelling, and, in infants, rouse from sleep. Rapid shifts between breathing at rest (eupnea) and sniffing point to generation of both behaviors by the core brainstem inspiratory oscillator, the preBotzinger Complex (preBotC). Eupneic rhythm generating mechanisms, when driven faster, are assumed to underlie higher frequency sniffing rhythms; however, the mechanisms governing sniffing have not been directly...

bioRxiv 9d ago