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Genomic-Adjusted Radiation Dose from Bulk RNA Sequencing for Personalized Radiotherapy

Radiotherapy is delivered to more than half of all patients with cancer yet is prescribed using uniform physical doses despite well-established interpatient variability in biological response. The genomic-adjusted radiation dose (GARD), derived from the radiosensitivity index (RSI), integrates tumor transcriptomics with radiation dose to estimate patient-specific treatment effect, and has been clinically validated as a predictor of radiotherapy benefit across diverse disease sites, including...

bioRxiv 11d ago

The best recent poetry – review roundup

Haunting the Black Air by Anthony Joseph; Selected Poems by Leontia Flynn; Sparrow on the Rooftop by Rachel Long; You Must Live: New Poetry from Palestine, edited by Jorie Graham; Melete by Jennifer Lee Tsai; Somebody Should Have Pressed Record by Galia AdmoniHaunting the Black Air by Anthony Joseph (Bloomsbury, £12.99) Joseph’s follow-up to the TS Eliot prize-winning Sonnets for Albert sees his poetic approach become more radical. He pays homage to avant garde writers such as Will Alexander...

The Guardian Culture 5d ago

Raves, Brecht and re-enacting Diana’s funeral: the White Hotel bows out as the north’s bravest music venue

​After 10 years of avant garde mayhem, the rough-diamond Salford venue is set to close. Its founders look back on their artistic free-for-all and explain how its spirit will continue‘The White Hotel is similar to the Highlander and Keith Richards. It’s immortal,” declares Austin Collings.

The Guardian Culture 14d ago

Swing Youth: In Nazi Germany, jazz was an act of defiance

In Nazi Germany, jazz was an act of defiance May 31, 2026The interwar Weimar Republic period is often referred to as a "Golden Age" of culture and creativity in Germany. It was a time when groundbreaking movements, from Bauhaus architecture and experimental cinema to avant-garde art and theater, flourished against the backdrop of economic catastrophe and extreme political polarization. In cities such as Berlin, where speakeasies, cabarets and hedonistic nightlife were the norm, a radical new...

Deutsche Welle 10d ago

The best recent poetry – review roundup

Haunting the Black Air by Anthony Joseph; Selected Poems by Leontia Flynn; Sparrow on the Rooftop by Rachel Long; You Must Live: New Poetry from Palestine, edited by Jorie Graham; Melete by Jennifer Lee Tsai; Somebody Should Have Pressed Record by Galia AdmoniHaunting the Black Air by Anthony Joseph (Bloomsbury, £12.99) Joseph’s follow-up to the TS Eliot prize-winning Sonnets for Albert sees his poetic approach become more radical. He pays homage to avant garde writers such as Will Alexander...

The Guardian UK 5d ago

Praggnanandhaa becomes first Indian to raid Carlsen's backyard, win Norway Chess title

Rameshbabu Praggnanandhaa, what have you done? Just this Thursday, Norway's national football team came up with an avant-garde Viking-themed photoshoot with their squad destined for the upcoming FIFA World Cup. With superstars like Erling Haaland and Martin Ødegaard donning the traditional Viking costumes and posing as if they were getting ready for another raid, the piece of work looks exquisite to the naked eye.

Times of India 4d ago

James Blood Ulmer, adventurous US guitarist and vocalist, dies aged 86

Musician who spliced jazz, funk and blues, including in a spell on a major label in the early 1980s, was celebrated as ‘fearless’ by his familyJames Blood Ulmer, the US guitarist celebrated for his avant garde splicing of jazz, blues and funk, has died aged 86.A statement on social media said he died on 3 June. “His music was fearless, and so was his spirit,” his family added in another statement.

The Guardian World 1d ago

James Blood Ulmer, adventurous US guitarist and vocalist, dies aged 86

Musician who spliced jazz, funk and blues, including in a spell on a major label in the early 1980s, was celebrated as ‘fearless’ by his familyJames Blood Ulmer, the US guitarist celebrated for his avant garde splicing of jazz, blues and funk, has died aged 86.A statement on social media said he died on 3 June. “His music was fearless, and so was his spirit,” his family added in another statement.

The Guardian UK 1d ago

No Glastonbury, no problem: Here are eight European music festivals you can still book this summer

Most of Europe's music festivals have sold out, but there are plenty you can still get tickets for across the continent. Primavera Sound is already in the rear-view mirror. Glastonburyis taking 2026 off for one of its regular fallow years.

Euronews 1d ago

From Schitt's Creek to Desi Bling: Is cringe-binge actually about self-care?

Anatomically, as human beings, we have existed for around 300,000 years. But if we are talking civilization, it began around 5000 to 6000 years ago. Since then, we have all been trying to balance our most primal urges with our societal-expected ones.

Times of India 6d ago