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T-GMP: Terrain-conditioned Generative Motion Priors for Versatile and Natural Humanoid Locomotion
arXiv:2606.06944v1 Announce Type: new Abstract: Achieving both anthropomorphic naturalness and robust terrain traversal remains a fundamental challenge in humanoid locomotion. Existing Reinforcement Learning (RL) approaches typically rely on fixed motion priors, limiting their adaptability to varying environments. We propose Terrain-conditioned Generative Motion Priors (T-GMP), a module that captures a terrain-conditioned latent motion manifold from a few expert state-terrain demonstrations...
Arteriolar GMP signaling revealed by FRET-based real-time measurement in vivo
cGMP evokes arteriolar vasorelaxation and is generated in smooth muscle by the soluble guanylyl cyclase (sGC) stimulated by endothelial NO. Phosphodiesterases (PDEs) degrade cGMP and may contribute in diameter regulation. We examined arteriolar cGMP levels in real-time in vivo upon NO and acetylcholine (ACh) and effects of PDE inhibition.
Benchmarking Local LLMs for Natural-Language-to-SQL Querying in Biopharmaceutical Manufacturing: An Empirical Benchmark on Consumer-Grade Hardware
arXiv:2606.01338v1 Announce Type: new Abstract: Biopharmaceutical manufacturing organizations operate under regulatory frameworks such as FDA guidance, EU Good Manufacturing Practice (GMP), and the EU AI Act, which can restrict the use of cloud-based artificial intelligence systems. Locally deployed large language models (LLMs) offer a privacy-preserving alternative, but their suitability for pharmaceutical manufacturing tasks remains underexplored. This study evaluates four open-source LLMs...
Armed police scrambled near Salford school over 'man with knife' as Taser deployed
Armed police scrambled near Salford school over 'man with knife' as Taser deployed Dramatic body-worn images from police showed the moment a suspect, in his 60s, was Tasered and fell to the ground in the Cadishead area of Salford while appearing to hold a knife Armed police were scrambled to a street near a school in Salford following reports of a man with a knife. Officers attended the incident on Liverpool Road in the Cadishead area at around 9am on Tuesday morning. Dramatic body-worn...
Wrongly jailed for 17 years Andrew Malkinson 'insulted' at 'violent, depraved' rapist's 'soft' sentence
Wrongly jailed for 17 years Andrew Malkinson 'insulted' at 'violent, depraved' rapist's 'soft' sentence Paul Quinn, 52, violently attacked a young mother in July 2003 - yet Andrew Malkinson was wrongly jailed a year later. He was only cleared in 2023 following a long campaign An innocent man who served 17 years behind bars for rape has said he is "insulted" after the real offender was handed a softer sentence than him.
Crime gang busted after 'highly sophisticated' mail order drug ring
Crime gang busted after 'highly sophisticated' mail order drug ring Iain Potter, Jack Wright and Ross Fathi have been jailed for running a 'highly sophisticated' mail-order drugs gang from a unit in Bury, Greater Manchester Three men have been jailed after police smashed a "highly sophisticated" mail-order drugs gang that used Royal Mail to distribute millions of pounds worth of narcotics across the UK. Iain Potter, Jack Wright and Ross Fathi ran the "industrial-scale" operation from a...
Oldham dad found dead in car days after going missing as tragic update issued
Oldham dad found dead in car days after going missing as tragic update issued A major search for Christopher Neary, 58, began after he was last seen by a neighbour and was reported missing in Oldham - his body has now been found inside a car A missing dad has tragically been found dead in a car in Oldham. A major search for Christopher Neary, 58, was launched last Thursday after he was last seen by a neighbour and was reported missing. He had left his flat on Lees New Road in the Oldham area...
Family pay tribute to woman found dead in suspected murder
Tributes have been paid to Keeley Aspinall, who was found dead in circumstances suspected
'It's only a matter of time' - locals fear death on road where people were 'thrown 30ft in the air'
'It's only a matter of time' - locals fear death on road where people were 'thrown 30ft in the air' Those living on Vulcan Street in Oldham, Greater Manchester have expressed their concern after Sharon McLean’s son was mowed down by a car and broke his leg Locals still fear the same road where Sharon McLean’s son was run over 26 years ago, believing it remains a place where further accidents are inevitable. “It happens all the time. Sometimes it’s bloody murder but what can you do about it?”
Police officer wept as he faced drug-driver who left him with life-changing injuries
Police officer wept as he faced drug-driver who left him with life-changing injuries Shaun Orchard, 23, has been jailed for three years and two months for crashing into a police vehicle and leaving PC Rushton with life-changing injuries in Stockport in April last year A cocaine and alcohol-fuelled driver who crashed into a police vehicle and left an officer with life-changing injuries has been jailed. Shaun Orchard, 23, was sentenced to three years and two months in prison after the...