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'Holy grail' blood test to help NHS diagnose different cancers fails in trial

'Holy grail' blood test to help NHS diagnose different cancers fails in trial NHS hopes dashed after trial of the first multi-cancer blood test it had hoped would revolutionise treatment - but scientists say all may not be lost Hopes that a “revolutionary” cancer blood test could soon be rolled out on the NHS have been dashed after a trial failed to achieve its main goal. The NHS had hoped to prove that the first multi-cancer blood test, which has been dubbed the “Holy Grail” for medical...

Daily Mirror 11d ago

GRAIL: Generating Humanoid Loco-Manipulation from 3D Assets and Video Priors

arXiv:2606.05160v1 Announce Type: new Abstract: Scaling humanoid loco-manipulation requires robot-compatible demonstrations across diverse objects, whole-body motions, and scene geometries, but teleoperation and motion capture are difficult to scale because each collection depends on physical setups, instrumented actors, and robot operation. We present GRAIL, a digital generation pipeline that remains fully virtual until deployment: it composes 3D assets, simulator-ready scenes, and priors...

arXiv CS 6d ago

FP8 is All You Need (Part 1): Debunking Hardware FP64 as the HPC Holy Grail

arXiv:2606.06510v1 Announce Type: new Abstract: Conventional HPC dogma holds that native hardware FP64 silicon is the irreducible foundation of scientific computing -- the "holy grail" of double-precision simulation. This paper argues the dogma is wrong: on AI-optimised GPUs of the B300 generation and beyond, abundant FP8 tensor throughput combined with the Chinese Remainder Theorem-based Ozaki Scheme II recovers memory-roof execution at full FP64 accuracy across the canonical HPC kernel...

arXiv CS 2d ago

GRAIL: Gradient-Reweighted Advantages for Reinforcement Learning with Verifiable Rewards

Announce Type: new Abstract: Reinforcement learning with verifiable rewards (e.g. GRPO) is now a common way to improve mathematical reasoning in Large Language Models (LLMs). However, current methods usually broadcast one sequence-level advantage to all tokens, or use costly process reward models (PRMs) for step-level supervision. Uniform advantage distribution assumes that all tokens contribute equally to the final reward.

arXiv CS 6d ago

Medieval King Arthur manuscript could fetch £2m at auction

A richly illuminated medieval manuscript containing early versions of the Merlin and Grail legends is set to be auctioned. The tome, which has been in private hands for over 700 years, features detailed illustrations, including Merlin as a shape-shifting stag and the Knights of the Round Table. Experts suggest the manuscript could fetch a price of £2 million at auction.

The Guardian World 15d ago

Medieval King Arthur manuscript could fetch £2m at auction

A richly illuminated medieval manuscript containing early versions of the Merlin and Grail legends is set to be auctioned. The tome, which features detailed illustrations such as Merlin as a shape-shifting stag and the Knights of the Round Table, has been kept in private hands for over 700 years. The manuscript is estimated to fetch around £2 million.

The Guardian UK 15d ago

Trial of multi-cancer blood test among 142,000 NHS patients fails to meet main aim

Results presented at oncology conference in Chicago show Galleri test failed to reduce late-stage cancer diagnosesA blood test for more than 50 types of cancer that was billed as the holy grail of oncology has failed to achieve its main objective in a major clinical trial, according to data presented at the world’s largest cancer conference. The goal of the study involving 142,000 NHS patients in the UK was to assess whether adding the multi-cancer early detection test Galleri to standard...

The Guardian UK 11d ago

Trial of multi-cancer blood test among 142,000 NHS patients fails to meet main aim

Results presented at oncology conference in Chicago show Galleri test failed to reduce late-stage cancer diagnosesA blood test for more than 50 types of cancer that was billed as the holy grail of oncology has failed to achieve its main objective in a major clinical trial, according to data presented at the world’s largest cancer conference. The goal of the study involving 142,000 NHS patients in the UK was to assess whether adding the multi-cancer early detection test Galleri to standard...

The Guardian Health 11d ago

Green growth claims are overstated—our study shows three reasons why

Green growth claims are overstated—our study shows three reasons why Lisa Lock Scientific Editor Andrew Zinin Lead Editor A holy grail of environmental policy is an economy that delivers prosperity without requiring the ever-increasing consumption of raw materials. Increasing incomes while reducing environmental pressures hinges on the "decoupling" of energy emissions from economic growth. Some countries in the global economy are moving in the right direction.

Phys.org 1d ago

Trial of multi-cancer blood test among 142,000 NHS patients fails to meet main aim

Results presented at oncology conference in Chicago show Galleri test failed to reduce late-stage cancer diagnosesA blood test for more than 50 types of cancer that was billed as the holy grail of oncology has failed to achieve its main objective in a major clinical trial, according to data presented at the world’s largest cancer conference. The goal of the study involving 142,000 NHS patients in the UK was to assess whether adding the multi-cancer early detection test Galleri to standard...

The Guardian World 11d ago