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Global Combinatorial Optimization

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Predicting Future Utility: Global Combinatorial Optimization for Task-Agnostic KV Cache Eviction

arXiv:2602.08585v2 Announce Type: replace Abstract: Given the quadratic complexity of attention, KV cache eviction is vital to accelerate model inference. Current KV cache eviction methods typically rely on instantaneous heuristic metrics, implicitly assuming that score magnitudes are consistent proxies for importance across all heads.

arXiv CS 8d ago

Regularized Large Neighborhood Search

Announce Type: new Abstract: Operations research practitioners typically tackle NP-hard combinatorial problems using large neighborhood search (LNS), a scalable heuristic that iteratively refines a current solution by locally re-optimizing subsets of its variables. In contrast, most existing approaches for integrating combinatorial optimization layers into neural networks still assume access to an exact global solution, which is computationally intractable. We bridge this gap by introducing...

arXiv CS 8d ago

Hybrid Metaheuristic Combining the Dragonfly Algorithm and Tabu Search for the Traveling Salesman Problem

Announce Type: new Abstract: The Traveling Salesman Problem (TSP) is a classical NP-hard combinatorial optimization problem that aims to find the shortest Hamiltonian cycle visiting each city exactly once and returning to the starting point. This paper proposes a hybrid metaheuristic for the TSP by combining the Dragonfly Algorithm (DA), a swarm-intelligence-based global search method, with Tabu Search (TS), a memory-based local search technique. The proposed method follows a High-Level...

arXiv CS 1d ago

Linear Ordering Problem: Time for a Change

arXiv:2605.31051v1 Announce Type: new Abstract: The Linear Ordering Problem (LOP) is a fundamental combinatorial optimization problem with important applications in areas such as economics, social choice, and machine learning. Its most prominent use is the triangulation of economic input-output tables, which helps identify critical industries in an economy.

arXiv CS 9d ago

Linear Ordering Problem: Time for a Change

arXiv:2605.31051v2 Announce Type: replace Abstract: The Linear Ordering Problem (LOP) is a fundamental combinatorial optimization problem with important applications in areas such as economics, social choice, and machine learning. Its most prominent use is the triangulation of economic input-output tables, which helps identify critical industries in an economy. Most existing algorithms have been evaluated on benchmarks derived from outdated macroeconomic data, which no longer reflect the...

arXiv CS 2d ago

Cosm: Collective Switched Motion for Fast and Accurate Sparse Ising Optimization

arXiv:2605.30355v1 Announce Type: new Abstract: We introduce Collective Switched Motion (Cosm), a heuristic algorithm for solving sparse Ising-type optimization problems. Cosm combines locally interacting continuous circular variables with global coordination rules that facilitate collective dynamics. Pairwise interactions occur sequentially over a set of conflict-free edge partitions, resulting in an interaction network that switches periodically.

arXiv CS 9d ago

Cosm: Collective Switched Motion for Fast and Accurate Sparse Ising Optimization

arXiv:2605.30355v1 Announce Type: cross Abstract: We introduce Collective Switched Motion (Cosm), a heuristic algorithm for solving sparse Ising-type optimization problems. Cosm combines locally interacting continuous circular variables with global coordination rules that facilitate collective dynamics. Pairwise interactions occur sequentially over a set of conflict-free edge partitions, resulting in an interaction network that switches periodically.

arXiv Physics 9d ago

HiTokSR: A Coarse-to-Fine Tokenizer with Hierarchical Codebooks for High-Fidelity Real-World Image Super-Resolution

arXiv:2606.01157v1 Announce Type: new Abstract: Vector-quantized (VQ) generative models have shown promising results in real-world image super-resolution (Real-ISR). However, existing methods typically rely on a monolithic latent space that entangles low-frequency structures with high-frequency textures. This entanglement forces a single codebook to capture a combinatorially complex set of structure-texture pairings, which constrains representational capacity and limits codebook utilization.

arXiv CS 8d ago

COMPOSE: Hypergraph Cover Optimization for Multi-view 3D Human Pose Estimation

Announce Type: replace Abstract: 3D human pose estimation from sparse multi-view camera rigs is an essential task for numerous applications, including action recognition, sports analysis, and human-robot interaction. While learned methods dominate the field on benchmarks, they require large annotated datasets; training-free optimization-based methods remain promising as they circumvent 3D supervision by solving a correspondence problem across views from 2D detections. Existing combinatorial...

arXiv CS 2d ago

Molecular glue degraders of HuR suppress BRAF-mutant colorectal cancer

Abstract BRAF gain-of-function mutations, particularly BRAF(V600E), affect roughly 10% of all patients with colorectal cancer (CRC), and portend poor prognosis with limited therapeutic interventions. BRAF inhibitors such as encorafenib are ineffective due to MAPK pathway reactivation driven by BRAF dimerization. Combined inhibition of BRAF and EGFR, although approved therapies, results in short survival benefits and frequent treatment resistance and relapse1,2,3.

Nature 18h ago