HCN

HCN channels enhance synchrony propagation in heterogeneous synfire chains

Motivation: Information flow and temporal coding in cortical circuits depend critically on the reliable transmission of precisely timed synchronous spike patterns. Although cortical assemblies achieve such transmission despite pronounced intrinsic heterogeneities and stochastic high-conductance states, the mechanisms underlying effective synchrony propagation under in vivo conditions remain poorly understood. Methodology: In this study, we address this gap using large-scale,...