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Related Articles from SNS
Acquired genetic and cell-state changes in IDH-mutant glioma progression
Nature, Published online: 03 June 2026; doi:10.1038/s41586-026-10612-6Longitudinal transcriptomic, chromatin and genomic analyses of the two types of IDH-mutant glioma reveal in detail how disease progression is influenced by interdependent genetic, epigenetic and microenvironmental factors.
Intra-slide calibration technology improves immunohistochemical harmonization within and between anatomic pathology laboratories
The reproducibility of immunohistochemistry in tumor tissue analysis across reference labs remains a persistent challenge. We tested the extent to which an intra-slide calibration technology mitigated discprepencies in inter-laboratory assays of p53 immunohistochemical (IHC) reactions in brain biopsies of glioblastoma (GB), IDH-wildtype. Intra-slide calibration technologies apply a 0-100% concentration scale incorporating primary surrogate and secondary antibodies to generate a standardized...
How Much MRI Preprocessing Is Enough? A Cost-Utility Study for Brain MRI Foundation Models
Announce Type: new Abstract: MRI preprocessing defines the input distribution seen by brain MRI foundation models, yet it is usually treated as routine data cleaning rather than a modeling choice. We ask how much preprocessing is worth its computational cost for self-supervised 3D MRI pretraining. Keeping the corpus, 3D ViT backbone, masking protocol, and downstream evaluations fixed, we compare a graded P0-P7 preprocessing spectrum for masked autoencoding (MAE) and joint-embedding...
'What a legacy': Pioneering researcher Richard Scolyer dies aged 59
Professor Richard Scolyer dies aged 59 leaving behind legacy of revolutionary brain cancer research Mon 8 Jun 2026 at 12:06am Former Australian of the Year Professor Richard Scolyer has died aged 59 after fighting the "worst of the worst brain cancers". His legacy: fast-tracking revolutionary cancer treatment by volunteering to be "patient zero" in a radical approach to treating his tumour. Scolyer fought the aggressive brain cancer for almost three years, defying the terrible survival odds.
'Never be forgotten': Tributes pour in for Richard Scolyer
Cancer expert Richard Scolyer remembered as loving family man making a difference to lives of patients Mon 8 Jun 2026 at 11:38am In short: Melanoma pathologist Richard Scolyer, who died from brain cancer, is being remembered by his family as a loving man. His brother-in-law read a statement on behalf of the family saying his passing has left a big hole in their lives. Prime Minister Anthony Albanese says Professor Scolyer's wife, Katie Nicholl, has accepted an offer for a state funeral.