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Quilting the Brain: Whole-Brain iEEG Reconstruction via Incomplete Observation Linear Mixed Models

Mapping human brain function at high spatiotemporal resolution is constrained by the physical limitations of non-invasive imaging and the sparse sampling of invasive electrophysiology. While intracranial electroencephalography (iEEG) captures local field potentials with millimeter precision, clinical implantation strategies result in a ``coverage paradox'': observations are restricted to disjoint, patient-specific patches, leaving most of the cortex unobserved. This study introduces the...

bioRxiv 7d ago