Interictal
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Related Articles from SNS
Slow Oscillations Gate Interictal Spikes Across the Human Thalamocortical-Epileptogenic Network
Background: Slow oscillations (SOs; 0.5-1.5 Hz), a hallmark of non-rapid eye movement (NREM) sleep, are associated with a marked amplification of interictal epileptiform spike (IIS) activity in focal epilepsy. However, the network-level organization of this effect across the thalamocortical-epileptogenic system, and whether IIS-permissive SOs can be predicted from pre-onset brain states, remain unclear. Methods: We analyzed simultaneous scalp EEG and stereo-EEG (SEEG) recordings from 6...