J. Liu
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Related Articles from SNS
Uniform-in-time Strong Error Estimates of Tamed-FEM to Superlinear SPDEs driven by Multiplicative Noise
arXiv:2606.09173v1 Announce Type: new Abstract: We establish sharp, uniform-in-time strong error estimates for a nonlinearity-explicit tamed finite element method (FEM) applied to a class of superlinear stochastic partial differential equations (SPDEs) driven by multiplicative noise, including the stochastic Allen--Cahn equation with a moderately thick interface. This tamed-FEM was first introduced in [Z. Liu and J. Shen, arXiv:2502.19117] to ensure long-time unconditional stability and to...
Mitochondria directly interact with the nuclear pore complex
Abstract Mitochondria regulate cellular processes through direct and indirect interactions with other organelles. A well-studied example has been contact with the endoplasmic reticulum at mitochondrial-associated endoplasmic reticulum membranes1, which control pathways including redox and calcium homeostasis2,3. Recent studies have also reported direct mitochondria–nuclear membrane contacts in cancer cells and yeast that promote pro-survival signalling4,5.
Scientists mapped every neural connection in a fruit fly and found a surprise
Scientists mapped every neural connection in a fruit fly and found a surprise Scientists have completed the first full brain-to-body wiring map of a fruit fly, revealing that behavior may be driven more by local neural teamwork than by a central brain command center. - Date: - June 10, 2026 - Source: - Harvard Medical School - Summary: - A groundbreaking new connectome maps every neural connection in an adult fruit fly’s central nervous system, creating an unprecedented view of how the brain...
A thalamus–brainstem attractor network drives history-biased decisions
Abstract Natural environments often change gradually, making it adaptive to bias decisions on the basis of the recent past — a phenomenon known as serial dependence1,2,3. Large-scale recordings during behaviour have identified that serial dependence is a common motif for decision-making, with neural representations of past experiences found throughout the brain4,5,6,7,8,9,10,11. However, it remains unclear whether this bias arises from dedicated neural circuits with history-specific...
Structural basis for chaperone-guided assembly of RNA-induced silencing complex
Abstract The RNA-induced silencing complex (RISC), comprising an Argonaute (AGO) protein and a small RNA, is the central effector in RNA silencing. Small RNAs are loaded onto AGO as bulky duplexes in an HSP70- and HSP90-dependent process1,2,3, but the molecular mechanism remains poorly understood. Here we identify the human AGO–HSP90–p23 complex, which captures AGO in an RNA-free state, termed the AGO maturation complex (AMC).
A remark on the majorizing measures theorem for general processes
arXiv:2606.03973v1 Announce Type: cross Abstract: We show that the lower bound in the majorizing measures theorem holds for a large class of random vectors. Specifically, suppose $X \sim \mu$ is a centered random vector in $\mathbf{R}^n$ with \[ C_{\mathrm{KL}}(\mu) = \sup_{\substack{\theta \neq \eta \\ \theta, \eta \in \mathbf{R}^n}} \frac{\mathrm{KL}(\mu_\theta \| \mu_\eta)}{\|\theta - \eta\|_2^2} <
A remark on the majorizing measures theorem for general processes
Announce Type: replace-cross Abstract: We show that the lower bound in the majorizing measures theorem holds for a large class of random vectors. Specifically, suppose $X \sim \mu$ is a centered random vector in $\mathbf{R}^n$ with \[ C_{\mathrm{KL}}(\mu) = \sup_{\substack{\theta \neq \eta \\ \theta, \eta \in \mathbf{R}^n}} \frac{\mathrm{KL}(\mu_\theta \| \mu_\eta)}{\|\theta - \eta\|_2^2} <
Diverse binding poses of agonistic neurotoxins on human Na<sub>v</sub>1.6
Abstract Voltage-gated sodium (Nav) channels are key targets of various venomous toxins. Deciphering the binding poses and mechanisms of action of representative toxins will help to dissect the functional mechanism of the channels and facilitate therapeutic development targeting Nav channels1,2. Here we present cryo-electron microscopy (cryo-EM) structures of distinct binding poses of three agonistic peptide toxins on the human Nav1.6–β1 channel complex.
Efficient and accurate neural-field reconstruction using resistive memory
Abstract Applications such as medical imaging, augmented and virtual reality, and embodied artificial intelligence (AI) depend on the ability to reconstruct complex signals from sparse observations. These applications are characterized by incomplete measurements and limited computational resources. Traditional approaches to digital hardware face the following challenges: explicit signal representations require heavy sampling and storage, data movement across the von Neumann bottleneck...
Doctors thought this kidney drug helped some patients. It may help millions more.
Doctors thought this kidney drug helped some patients. It may help millions more. - Date: - June 8, 2026