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Fox ecstatic after winning first World Cup gold since surgery
Jessica Fox won gold in the women's K1 event at the ICF Canoe Slalom World Cup in Prague, Czechia. Fox was competing in only her second World Cup event since returning to international competition. She had surgery to remove a benign tumour from her left kidney last year.
ESF links kindergartens to primary schools, securing places through to graduation
Hong Kong’s biggest international school group has rolled out a “through-train” arrangement, linking all its kindergartens to its primary schools from September next year and guaranteeing pupils a place all the way to secondary graduation. The English Schools Foundation (ESF) said on Friday that starting next academic year, all its kindergartens would, for the first time, be directly linked to ESF primary schools. Families applying for a K1 place for the 2027-28 school year this September...
Trust Region On-Policy Distillation
Announce Type: replace Abstract: On-Policy Distillation (OPD) is a fundamental technique for efficient post-training of large language models (LLMs), with broad applications in agent learning, multi-task enhancement, and model compression. However, OPD training becomes unstable when the teacher and student distributions differ substantially, as teacher supervision on student-generated tokens may yield unreliable policy gradients and even cause optimization failure. This work addresses...
The KNN rollercoaster: from bulk ceramics to phase engineered wafer-scale thin films
Announce Type: cross Abstract: Since the initial disclosure of the extraordinary piezoelectric coefficients of Potassium sodium niobate (KNN) in near-equimolar bulk ceramics, its development trajectory has resembled a rollercoaster, with its integration into microelectronics severely lagging due to thermodynamic stability issues and poor planar process compatibility. In this work, we revisit the bulk-derived phase diagram for the specific case of thin films integrated on silicon. By...
Trust Region On-Policy Distillation
Announce Type: new Abstract: On-Policy Distillation (OPD) is a fundamental technique for efficient post-training of large language models (LLMs), with broad applications in agent learning, multi-task enhancement, and model compression. However, OPD training becomes unstable when the teacher and student distributions differ substantially, as teacher supervision on student-generated tokens may yield unreliable policy gradients and even cause optimization failure. This work addresses reliable...
Molecular glue degraders of HuR suppress BRAF-mutant colorectal cancer
Abstract BRAF gain-of-function mutations, particularly BRAF(V600E), affect roughly 10% of all patients with colorectal cancer (CRC), and portend poor prognosis with limited therapeutic interventions. BRAF inhibitors such as encorafenib are ineffective due to MAPK pathway reactivation driven by BRAF dimerization. Combined inhibition of BRAF and EGFR, although approved therapies, results in short survival benefits and frequent treatment resistance and relapse1,2,3.