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Clinical isolates of Mycobacterium avium complex reveal an M. intracellulare-associated IL-17/neutrophilic pulmonary immune program in a murine disease model

Mycobacterium avium complex (MAC) is the leading cause of nontuberculous mycobacterial pulmonary disease (NTM-PD) and mainly comprises M. avium (MAV) and M. intracellulare (MI). Host-pathogen interactions may contribute to the heterogeneous clinical course of MAC pulmonary disease (MAC-PD); however, species- or isolate-associated differences in virulence and host immune responses induced by MAC strains remain poorly understood. Here, we established a panel of MAC clinical isolates exhibiting...

bioRxiv 10d ago

Dual Quaternion-Based Unscented Kalman Filter with Visual Inertial Odometry for Navigation in GPS-Denied Environments

Announce Type: new Abstract: Reliable navigation in GPS-denied environments remains a fundamental challenge in robotics, aerospace, and autonomous vehicle applications. This paper presents a Dual Quaternion-Based Unscented Kalman Filter (DQUKF) equipped with a Visual Inertial Odometry (VIO) algorithm for accurate state estimation enabling navigation in GPS denied locations. The proposed framework formulates the DQUKF in an error state manner, where the nominal pose is represented by a unit...

arXiv CS 1d ago

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