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MEIS2

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Evolution and mechanism of MEIS2-mediated forelimb specialization in bats

The genomic basis of limb adaptations in tetrapods is thought to be largely driven by changes in gene regulation. However, the mechanisms by which regulatory programs evolve are not well understood. In bats, wing membrane development has been shown to be associated with expression of the transcription factor MEIS2 in the interdigital tissue of the forelimb.

bioRxiv 7d ago