MELAS
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I wore bright colours in a sea of navy and black - Founder on 20 years of Belfast Mela
Nisha Tandon moved to Northern Ireland during the Troubles and went on to found one of the country's biggest annual celebrations of cultural diversity.
Cell free-mtDNA release drives pyroptosis and inflammation in cell models carrying the mitochondrial m.3243A>G pathogenic variant
Mitochondrial Encephalopathy, Lactic Acidosis, and Stroke-like episodes (MELAS) syndrome is primarily caused by the heteroplasmic m.3243A>G/MT-TL1 pathogenic variant. Patients exhibit elevated circulating cell-free mtDNA (cf-mtDNA) in plasma, which acts as a damage-associated molecular pattern. Using patient-derived fibroblasts and neuronal progenitors, as well as transmitochondrial cytoplasmic hybrids (cybrids), we show that mutant cells release higher levels of cf-mtDNA than wild-type...
Mamdani skips Israel Day Parade despite joining other cultural celebrations
New York Mayor Zohran Mamdani won't be attending the city's annual Israel Day Parade on Sunday, a break from decades-long tradition, despite attending other events celebrating the city's diverse cultural landscape.Since 1964, every mayor in the city has attended the Jewish celebration, which comes amid record levels of antisemitism and weeks of anti-Israel demonstrations outside synagogues and Jewish communal institutions across New York.Despite his absence, the mayor pledged to provide...
Drishti AI-Event Guardian: An Intelligent Real-Time Crowd Monitoring and Emergency Response System for Mass Gathering Events
Announce Type: new Abstract: Mass gathering events are associated with critical safety incidents caused by insufficient crowd monitoring and inadequate emergency response coordination. Traditional surveillance systems lack intelligent analytics, resulting in delayed threat identification, poor resource deployment, and weak support for vulnerable individuals during dense public assemblies. This paper presents Drishti AI-Event Guardian, an intelligent crowd management framework using deep...
‘Nobody wants to see another Ram’: Arun Govil speaks on backlash over Ranbir Kapoor's ‘Ramayana’
Among the most eagerly awaited films of the year is the ambitious ‘ Ramayana’, helmed by director Nitesh Tiwari and led by Ranbir Kapoor in the titular role of Lord Rama. Sai Pallavi plays Sita while Yash steps into the formidable role of Ravana. Adding a special touch to the project is the casting of veteran actor Arun Govil, who is forever etched in the hearts of millions of Indians for his legendary portrayal of Lord Rama in Ramanand Sagar's iconic television series Ramayan.