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South Africa rolls out new preventive HIV shot in 'major turning point'
In a potentially major advancement in the fight against HIV and AIDS, a South African laboratory is set to produce a generic version of a new preventive treatment that is injectable, and only needs to be administered twice a year. Initial studies show it reduces the risk of transmission by around 99.9%. FRANCE 24's Eunice Masson tells us more from Cape Town.
FRANCE 24 journalists forced to sign NDA after asking about open letter against media mogul Bolloré
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Mutation-dependent responses to sleep and exercise in clonal haematopoiesis
Abstract Clonal haematopoiesis (CH) activates inflammation and increases the risk of atherosclerosis1,2. Whether lifestyle alters CH clone expansion or the phenotypic programming of CH mutant cells, thereby affecting atherosclerosis, is unknown. Here, in humans and mice and across mutations in Jak2, Tet2, Trp53 and Dnmt3a, we demonstrate mutation-dependent responses to sleep and exercise in CH and show that mutant cells are uniquely sensitive to lifestyle.
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