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p38 dependent IL-33 responses define a conserved inflammatory programme in mast cells

Interleukin-33 (IL-33) is a key cytokine in mast cell mediated immunity, promoting inflammatory cytokine production without inducing degranulation. Here, we compared IL-33 induced proteomic responses across three mast cell culture systems, Foetal Liver derived Mast Cells (FLMCs), Bone Marrow derived Mast Cells (BMMCs), and Peritoneal Mast Cells (PMCs), using quantitative data-independent acquisition mass spectrometry. Although baseline proteomes were largely conserved across all mast cell...

bioRxiv 9d ago

Black suburbanization is reshaping American neighborhoods, study finds

Black suburbanization is reshaping American neighborhoods, study finds Lisa Lock Scientific Editor Andrew Zinin Lead Editor In 1970, nearly half of all Black individuals in the U.S. resided in a large city. Over the past 50 years, that number has fallen to merely 25%, while the share living in the suburbs of large cities rose from 16% to 36%.This demographic shift is as large as the post-World War II wave of the Great Migration, according to economists Evan Mast of the University of Notre...

Phys.org 6d ago

TokaMind: A Multi-Modal Transformer Foundation Model for Tokamak Plasma Dynamics

Announce Type: replace-cross Abstract: We present TokaMind, to our knowledge the first open-source foundation model for tokamak plasma dynamics, based on a Multi-Modal Transformer (MMT) and pretrained on heterogeneous diagnostics from the publicly available MAST dataset. TokaMind supports multiple data modalities (time-series, 2D profiles, and videos) with different sampling rates, robust missing-signal handling, and efficient task adaptation via selectively loading and freezing four model...

arXiv CS 2d ago

TokaMind: A Multi-Modal Transformer Foundation Model for Tokamak Plasma Dynamics

Announce Type: replace Abstract: We present TokaMind, to our knowledge the first open-source foundation model for tokamak plasma dynamics, based on a Multi-Modal Transformer (MMT) and pretrained on heterogeneous diagnostics from the publicly available MAST dataset. TokaMind supports multiple data modalities (time-series, 2D profiles, and videos) with different sampling rates, robust missing-signal handling, and efficient task adaptation via selectively loading and freezing four model...

arXiv Physics 2d ago

Reporter's Notebook: Tlaib forces rare House procedure after Republican accuses her of defending terrorists

"That term of art may not mean much off Capitol Hill. But it’s a phrase which usually signals there’s a ruckus in the House of Representatives. The House witnessed one such melee recently.

Fox News Politics 2d ago

Reporter's Notebook: Tlaib forces rare House procedure after Republican accuses her of defending terrorists

"That term of art may not mean much off Capitol Hill. But it’s a phrase which usually signals there’s a ruckus in the House of Representatives. The House witnessed one such melee recently.

Fox News 2d ago

SEE IT: House floor erupts after GOP lawmaker accuses Tlaib of Hezbollah ties

The House floor erupted into chaos Wednesday after Rep. Max Miller, R-Ohio, accused Rep. Rashida Tlaib, D-Mich., of having ties to terrorist groups, including Hezbollah. The shouting match came during a heated debate over a resolution that would force President Donald Trump to withdraw U.S. forces from Lebanon. Tlaib, a progressive lawmaker and member of the Squad, is expected to force a vote on the measure Thursday, arguing that the United States should not assist Israel’s war in Lebanon.

Fox News 6d ago

SEE IT: House floor erupts after GOP lawmaker accuses Tlaib of Hezbollah ties

The House floor erupted into chaos Wednesday after Rep. Max Miller, R-Ohio, accused Rep. Rashida Tlaib, D-Mich., of having ties to terrorist groups, including Hezbollah. The shouting match came during a heated debate over a resolution that would force President Donald Trump to withdraw U.S. forces from Lebanon. Tlaib, a progressive lawmaker and member of the Squad, is expected to force a vote on the measure Thursday, arguing that the United States should not assist Israel’s war in Lebanon.

Fox News Politics 6d ago

Democrats split over Tlaib's Lebanon measure as Republicans seize on Hezbollah omission

Democrats splintered over a resolution seeking to block the U.S. from assisting Israel's war against Hezbollah, an Iranian-backed terrorist group, on Thursday. The measure, offered by progressive Rep. Rashida Tlaib, D-Mich., would require President Donald Trump to withdraw U.S. forces from Lebanon. For months, Israel and Hezbollah, a U.S.-designated terrorist group and Iranian proxy, have been at war in southern Lebanon, but the United States has not joined the conflict.

Fox News 5d ago