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Variable zinc concentrations among commercially available Mueller-Hinton Broth brands affects SIR interpretations during broth microdilution in vitro antimicrobial susceptibility testing with the novel metallo-beta-lactamase inhibitor APC148
The well-known discrepancy between the in vitro and in vivo efficacy of {beta}-lactam antibiotics in metallo-{beta}-lactamase (MBL) containing Gram-negative bacteria has during recent years been found to be at least partially explained by zinc levels at infection sites being much lower than those found in conventional cation-adjusted Mueller-Hinton Broth (caMHB) media used for in vitro susceptibility testing. Previous studies have also demonstrated that a high variability exists with respect...
Goldman’s Mueller-Glissman Sees Healthy Pullback in Tech Rally
Traders work on the floor of the New York Stock Exchange. Photographer: Michael Nagle/Bloomberg
Unlocking 'the true space age': Impulse Space raises $500 million to build out fleet of ultra-mobile spacecraft
Unlocking 'the true space age': Impulse Space raises $500 million to build out fleet of ultra-mobile spacecraft Impulse Space just got a lot more money to help finance its big ambitions in the final frontier. The California-based company — which was founded in 2021 by propulsion expert Tom Mueller, the first person Elon Musk ever hired at SpaceX — announced today (June 2) that it has raised $500 million in a "Series D" investment round. It will use the funds to scale up the production and...
Impulse Space raises $500 million as orbital maneuvering race heats up
Getting around space, as it turns out, is kind of a big deal. On Tuesday, Impulse Space, a company dedicated to improving space mobility, announced it has raised $500 million in Series D funding. Since it was founded five years ago by SpaceX veteran Tom Mueller, the company has now raised more than $1 billion.
Impulse Space raises $500 million at $4.26 billion valuation as space investing surges
Impulse Space raises $500 million at $4.26 billion valuation as space investing surges NEW YORK, June 2 : Impulse Space, a startup building spacecraft that can ferry satellites and other payloads around in orbit after launch, said on Tuesday it has raised $500 million in a Series D funding round. The funding round values the company at $4.26 billion, according to a person familiar with the matter. The company was founded by Tom Mueller, SpaceX's first employee and the propulsion engineer who...
Leveraged ETF assets double in two months as investors press AI bet
Assets in leveraged ETF nearly doubled over two months, as investors scrambled for maximum exposure to the artificial intelligence trend. "Investors increasingly use leveraged instruments linked to the 'AI-trade' – assets in leveraged ETFs linked to AI and Tech themes have surged, with exposures in the US and Korea/Taiwan rising sharply- more than doubling in recent months," wrote Goldman's Christian Mueller-Glissmann in a note. Goldman cited data from EPFR tracking 573 leveraged U.S. equity...
Amplified Arctic iceberg traffic reshapes benthic biodiversity
Abstract The Arctic is undergoing rapid warming, resulting in retreating sea ice and glaciers1, yet how cryospheric changes propagate into the deep ocean remains poorly understood2. Here we identify a climate-driven mechanism linking accelerating glacier disintegration to an increase in deep-sea hard-bottom habitats far beyond calving fronts. Seafloor observations in Fram Strait show a localized increase in the density and patchiness of dropstones delivered by debris-laden icebergs.
The Y chromosome is home to surprising jumping genes
The Y chromosome is home to surprising jumping genes Stephanie Baum Scientific Editor Robert Egan Associate Editor The humble Y chromosome may be the smallest chromosome in the mammalian genome (and getting even smaller), but it is mighty: Genes on the Y chromosome are critical for fertility in males. In a new study in the journal Current Biology, researchers at the University of Michigan Medical School have studied deer mice to outline how the Y chromosome defends itself against decay by...
Measurement of reactor neutrino oscillation with the first JUNO data
Abstract Neutrino oscillations (see refs. 1,2 and references therein), a quantum effect manifesting at macroscopic scales, are governed by lepton flavour mixing angles and neutrino mass-squared differences3 that are fundamental parameters of particle physics, representing phenomena beyond the Standard Model. Precision measurements of these parameters are essential for testing the completeness of the three-flavour framework, determining the mass ordering of neutrinos and probing possible new...
Popular joint supplement glucosamine linked to faster Alzheimer’s progression
Popular joint supplement glucosamine linked to faster Alzheimer’s progression - Date: - June 10, 2026 - Source: - UF Health - Summary: - A major study suggests glucosamine, a popular supplement for joint pain, could be linked to faster progression from mild cognitive impairment to Alzheimer’s disease. Researchers found a 25% higher likelihood of developing dementia among glucosamine users and uncovered biological clues that may explain why. - Share: A widely used supplement marketed for...