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Cross-modal linkage risk in clinical vision-language models
arXiv:2606.02276v1 Announce Type: new Abstract: Vision-language models (VLMs) trained on paired chest radiographs and radiology reports learn a shared embedding space that can preserve instance-level image-report correspondence. This poses a privacy risk in settings where radiographs and reports are deliberately kept separate after acquisition, such as image-only data sharing or access-controlled reports, because a de-identified image may be re-linked to its original narrative report through...
A prognostic human brain network for diffuse midline glioma
Abstract Diffuse midline gliomas (DMGs) are near-universally lethal tumours of the childhood central nervous system1,2. In animal models, DMGs form brain-wide integrated networks through neuron-to-glioma synapses3,4,5,6 and glioma-to-glioma gap junctional coupling3. This extensive connectivity robustly promotes the growth and invasion of DMG3,4,5,6,7,8,9 and other glial malignancies10,11,12 through paracrine mechanisms and direct neuron-to-glioma synapses.
The World's Fastest Matching Engine Algorithm
arXiv:2606.01183v2 Announce Type: replace Abstract: A single CPU core sustains 32 million order messages per second at sub-microsecond median wire-to-wire latency, up to 11 times faster than the best open-source matching engines on identical hardware. Scaled out, a single 96-core commodity server (~$1,630/month) sustains ~640 million messages per second across 10,000 symbols, over 20 times the provisioned capacity of the U.S. consolidated quote feed. We reach these numbers by attacking the...
The U.S. Is Winging This Ebola Outbreak
By the time African health officials confirmed the world’s latest Ebola outbreak, the epidemic had already spilled from the Democratic Republic of the Congo into neighboring Uganda. Within two days, the World Health Organization declared the outbreak a public-health emergency of international concern. Less than two weeks later, the potential case count has risen past 1,000, including more than 230 deaths, and 10 other African countries have been designated at risk of being swept into the...
Gooey: A GPU-accelerated UI framework for Zig
A GPU-accelerated UI framework for Zig, targeting macOS (Metal), Linux (Vulkan/Wayland), and Browser (WASM/WebGPU). Join the Gooey discord Early Development: API is evolving. Example app built with Gooey — chat-zig, an Anthropic Claude client using the Zig 0.16 std.
Whole-genome duplication shaped cell-type evolution in the vertebrate brain
Abstract The complex brains of vertebrates have more cell types than those of their closest relatives. Whole-genome duplications (WGDs) occurred during early vertebrate evolution1, but it is unclear whether the duplicated genes (ohnologues) facilitated cell-type evolution. Here using brain single-cell transcriptomes from five chordates—human2, mouse3, lizard4, lamprey5 and amphioxus—we report that many cell-type families with conserved core transcription factors in vertebrates do not show...
Amplified Arctic iceberg traffic reshapes benthic biodiversity
Abstract The Arctic is undergoing rapid warming, resulting in retreating sea ice and glaciers1, yet how cryospheric changes propagate into the deep ocean remains poorly understood2. Here we identify a climate-driven mechanism linking accelerating glacier disintegration to an increase in deep-sea hard-bottom habitats far beyond calving fronts. Seafloor observations in Fram Strait show a localized increase in the density and patchiness of dropstones delivered by debris-laden icebergs.
Aperon Technical Report: Hierarchical No-Pointer Tangent-Local Search for High-Dimensional Approximate Nearest Neighbors
arXiv:2606.08813v1 Announce Type: new Abstract: We present HNTL (Hierarchical No-pointer Tangent-Local), the core vector indexing and candidate generation framework of the Aperon vector memory system. Proximity graphs (e.g., HNSW) incur a heavy pointer tax in memory overhead and induce irregular memory accesses that stall CPU pipelines. HNTL resolves this by partitioning the high-dimensional space into local, coherent grains, representing vectors as low-dimensional coordinates on local...
Deep learning four decades of human migration
Abstract Human migration is a fundamental driver of global demographic change, shaping population structure, labour markets and social policy across countries1,2,3. Although long-term migration patterns are often linked to economic development4, they can shift rapidly in response to shocks such as conflict, environmental crises and political change5. Despite its importance, migration remains difficult to measure consistently: existing data are sparse, concentrated in high-income settings and...
Gene ancestries reveal diverse microbial associations during eukaryogenesis
Abstract The origin of eukaryotes remains a central enigma in biology1. Continuing debates agree on the pivotal role of a symbiosis between an alphaproteobacterium and an Asgard archaeon2,3. However, the nature, timing and contributions of other potential bacterial partners4,5,6 and the role of interactions with viruses7,8,9 remain contentious.