N5 N6a

Quantum transport in mitochondrial complex I is governed by a conserved structural bottleneck

Electron transport in mitochondrial complex I is mediated by a chain of redox centers, yet how electrons traverse this network beyond the canonical pathway remains unclear. While prior models treat transport as a sequential process, they do not resolve whether alternative pathways contribute to functional electron flow. Here, we formulate electron transport as a continuous-time quantum walk on a structure-derived redox network and systematically map pathway-level electron flux inferred from...