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Trump's gold standard science is harming US science and health
On 29 May 2026, the US White House's Office of Management and Budget (OMB) proposed a rule that directs political appointees to require adherence with “gold standard science” in the awarding of federal grants, including research grants funded by the National Institutes of Health (NIH) and the National Science Foundation.1 This process, if finalised, would permit political appointees - officials placed in senior leadership or policy roles through a political appointment process, such as the...
Alveolar niche disruption and aberrant epithelial reprogramming are early hallmarks of idiopathic pulmonary fibrosis
Idiopathic pulmonary fibrosis (IPF) is a progressive interstitial lung disease in which the earliest cellular events driving fibrosis remain poorly defined. Here, we analyzed lung samples from three independent and unique cohorts of patients with early disease and preserved lung function (Florence, NIH, Forli), applying an integrated multimodal approach combining single-nucleus RNA sequencing, bulk transcriptomics, immunostaining, and spatial transcriptomics. Single-nuclear RNA sequencing of...
Researchers 'tried to smuggle vials of MPox and human DNA on packed commercial flight from Congo'
Researchers 'tried to smuggle vials of MPox and human DNA on packed commercial flight from Congo' Vincent Munster and Claude Kwe, National Institute of Health (NIH) researchers from the Netherlands and Cambodia, have been accused of trying to smuggle Mpox into the US A pair of researchers have been detained and charged with conspiracy to smuggle after they were allegedly captured at a major airport with vials containing the mpox virus and human DNA. Vincent Munster, 53, and Claude Kwe, 38,...
Federal workers experiencing ‘PTSD-like symptoms’ after unlawful firings by Trump administration
In survey of more than 300 fired probationary employees, 95% reported continuing mental health effectsUS federal workers laid off by the Trump administration said they are experiencing mental health effects, including PTSD-like symptoms, from losing their jobs, according to a new survey. More than 300 fired probationary employees were surveyed, with 95% reporting ongoing mental health effects, according to 27UNIHTED, a network of former National Institute of Health (NIH) employees. Nearly...
Trump administration has its sights set on destroying international research collaborations
In the latest chapter in the Trumpian destruction of US science, the White House Office of Management and Budget proposed troubling changes that affect how the federal government handles research grants, including those funded by the National Institutes of Health (NIH). Under these new rules, every federal research funding decision is subject to review by political appointees, who will be given the power to override decisions made on the basis of scientific merit.1 The traditional form of...
Scientists discover why Ozempic and Wegovy weight loss eventually plateaus
New NIH research reveals that semaglutide sparks different responses inside appetite-controlling brain cells, offering fresh insight into why GLP-1 weight-loss drugs don’t work the same for everyone. Scientists also found a possible way to extend the drugs’ effects, potentially helping patients push past weight-loss plateaus.
Federal workers experiencing ‘PTSD-like symptoms’ after unlawful firings by Trump administration
In survey of more than 300 fired probationary employees, 95% reported continuing mental health effectsUS federal workers laid off by the Trump administration said they are experiencing mental health effects, including PTSD-like symptoms, from losing their jobs, according to a new survey. More than 300 fired probationary employees were surveyed, with 95% reporting ongoing mental health effects, according to 27UNIHTED, a network of former National Institute of Health (NIH) employees. Nearly...
Republicans are trying to kill science in this country
Researchers say the Trump administration is finding new ways to punish science Standing in his laboratory, Harvard professor Sean Eddy gazes at a row of vacant work stations. More than a year ago, this lab was filled with over a dozen researchers. On a given day they might be working independently on analyzing genomic sequencing or gathered around the group table, drinking coffee and helping each other troubleshoot questions about genomic data from different species.
Mitochondria directly interact with the nuclear pore complex
Abstract Mitochondria regulate cellular processes through direct and indirect interactions with other organelles. A well-studied example has been contact with the endoplasmic reticulum at mitochondrial-associated endoplasmic reticulum membranes1, which control pathways including redox and calcium homeostasis2,3. Recent studies have also reported direct mitochondria–nuclear membrane contacts in cancer cells and yeast that promote pro-survival signalling4,5.
2 researchers charged with smuggling mpox into the US
Federal law enforcement agencies on Tuesday charged two researchers at a National Institutes of Health lab in Montana with conspiracy to smuggle deactivated mpox virus into the United States and with giving false statements about it. The researchers are Vincent Munster, an award-winning scientist who heads the virus ecology section at the Rocky Mountain Laboratories in Hamilton, Montana, a small town an hour’s drive south of Missoula, and Claude Kwe, a research fellow in Munster’s...