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Aberrant chromatin remodeling influences human neural cell fate change in Trisomy 21
Correct neural progenitor cell (NPC) fate specification is essential to produce the full complement of neurons and glia needed for proper brain structure and function. Neurodevelopmental disorders, including the autosomal aneuploidy Down syndrome (DS), or Trisomy 21 (T21), are frequently associated with impaired cell fate decisions which ultimately drive differences in overall brain size and cell type composition through unknown mechanisms. To uncover mechanisms driving altered NPC fate in...
AI Level of Detail: Distance-Aware ML Model Precision Selection for Real-Time Human Motion Prediction in Games
Announce Type: new Abstract: Modern game engines spend significant compute animating NPCs with learned motion models. This paper proposes AI Level of Detail (AI LOD), a framework in which machine learning inference precision is adapted based on the distance between each NPC and the player camera. The core idea mirrors classical geometry LOD: substitute a cheaper approximation where the difference is imperceptible.
Theos: Cities of Myth is the spiritual successor to the one of the great city builders of the early 2000s
Theos: Cities of Myth is the spiritual successor to the one of the great city builders of the early 2000s The game arrives later this year on PC. If you're a PC gamer of a certain age, you may fondly remember Impressions Games.
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An Integrated Techno-Economic Framework for Optimal Microgrid Design: An Australian Case Study
arXiv:2606.03783v1 Announce Type: new Abstract: Reliable and affordable electricity supply remains a challenge for remote and regional communities, motivating the deployment of renewable-based microgrids supported by flexible storage and advanced planning methods. This paper proposes an integrated techno-economic framework for optimal microgrid design and robustness assessment, and applies it to a 1000-household residential community in Rockhampton, Queensland (Australia). The framework...
Wholesome Direct returns June 6 with a slew of joyful games
Wholesome Direct returns June 6 with a slew of joyful games The hype is steadily building around Summer Game Fest 2026 and the show's June calendar is starting to fill out. The fine folks at Wholesome Games will host their seventh annual digital showcase on Saturday, June 6 at 12PM ET on YouTube and Twitch, featuring more than 50 joyful and just plain adorable games from new and established studios alike.
Hanson takes the stage as Chalmers's budget woes roll on
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The criticism Marc Fennell always gets for Stuff the British Stole
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Physics-Informed Modeling and Control of Emergent Behaviors in Robot Swarms
arXiv:2606.01597v1 Announce Type: new Abstract: Robot swarms can exhibit coherent collective behaviors through local perception, limited communication and decentralized decision-making, yet modeling and controlling such emergence remains challenging when behaviors unfold over multiple phases. Here we introduce PhySwarm, a physics-informed micro--macro framework that represents multi-stage swarm emergence as physically constrained density-field evolution coupled to executable robot motion. At...