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Researchers discover how to turn one germ's drug resistance into an Achilles' heel
Researchers discover how to turn one germ's drug resistance into an Achilles' heel Lisa Lock Scientific Editor Andrew Zinin Lead Editor Decades of reliance on the antibiotic rifampicin have fueled the rise of drug-resistant Mycobacterium tuberculosis (Mtb). But as the bacterium mutates to protect itself from the drug, it also creates new weak points that other therapies could exploit. Now, a new study published in Nature Microbiology shows that the most common rifampicin-resistance mutation...
Daily briefing: Trial to ‘de-age’ cells treats first person
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Green space exposure, mental health and the nasal microbiome explored
Green space exposure, mental health and the nasal microbiome explored Gaby Clark Scientific Editor Robert Egan Associate Editor Plenty of studies have linked exposure to nature to a wide variety of health benefits, from improved cognitive function to lower blood pressure to better mental health. Other research has found connections between the human microbiome and time spent outside. But an overlooked, understudied player in that connection is the assemblage of microbes found in the nose, or...
Redesigning an elusive bacterial enzyme into an efficient green catalyst
Redesigning an elusive bacterial enzyme into an efficient green catalyst Sadie Harley Scientific Editor Robert Egan Associate Editor Industrial oxidation chemistry is a cornerstone of modern manufacturing, accounting for nearly one-third of all chemical industrial processes. While essential for making pharmaceuticals, dyes, and many specialty chemicals, industrial oxidation typically relies on high-temperature, high-pressure processes involving toxic oxidizing agents. This has motivated...
Count Anything
arXiv:2605.30846v1 Announce Type: new Abstract: Object counting remains fragmented across domain-specific datasets and task formulations, despite rapid progress in generalist vision models. Existing counting models are often tailored to scenarios such as crowds, vehicles, cells, crops, or remote-sensing objects, and thus struggle to generalize across categories, visual domains, object scales, and density distributions. In this paper, we study text-guided object counting across domains, where...
Ötzi the Iceman and his microbiome—a 5,300-year-old relationship
Ötzi the Iceman and his microbiome—a 5,300-year-old relationship Stephanie Baum Scientific Editor Robert Egan Associate Editor Researchers at Eurac Research have obtained a detailed picture of the microbial community associated with Ötzi, Europe's oldest known natural human mummy. The study provides insights into a complex microbiome, ranging from the gut flora of a Copper Age human to cold-adapted yeasts. Using a variety of samples and methods, the researchers were able to differentiate...
Antibiotics drive resistance in waterways—even after they break down
Antibiotics drive resistance in waterways—even after they break down Gaby Clark Scientific Editor Robert Egan Associate Editor Antibiotics continue to drive resistance in bacteria, even after they are broken down in wastewater treatment plants and discharged into rivers and seas, new research published on World Oceans Day has shown for the first time. When we take antibiotics, around 90% of the drug passing through our bodies goes into toilets and ends up in sewage. Previous research has...