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Non-Rapid Eye Movement

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SleepExplain: Explainable Non-Rapid Eye Movement and Rapid Eye Movement Sleep Stage Classification from EEG Signal

arXiv:2606.07351v1 Announce Type: new Abstract: Classification of sleep stages is one of the most important diagnostic approaches for a variety of sleep-related disorders. Electroencephalography (EEG) is regarded as a powerful tool for examining the association between neurological effects and sleep phases since it correctly identifies sleep-related neurological alterations. During Non-Rapid Eye Movement (NREM) and Rapid Eye Movement (REM) sleep phases, a number of nerve and bodily functions...

arXiv CS 2d ago

Resonance-driven enhancement of sleep spindles using thalamic temporal interference stimulation

Sleep spindles are hallmarks of non-rapid eye movement sleep and support memory consolidation, yet remain difficult to modulate non-invasively. Combining computational modeling and human sleep recordings, we show that thalamus-targeted temporal interference stimulation (TIS) with a 5Hz envelope increases spindle density via subthreshold resonance in thalamocortical relay neurons. Our results demonstrate a mechanistic framework for the rational design of interventions to selectively augment...

bioRxiv 8d ago

Slow Oscillations Gate Interictal Spikes Across the Human Thalamocortical-Epileptogenic Network

Background: Slow oscillations (SOs; 0.5-1.5 Hz), a hallmark of non-rapid eye movement (NREM) sleep, are associated with a marked amplification of interictal epileptiform spike (IIS) activity in focal epilepsy. However, the network-level organization of this effect across the thalamocortical-epileptogenic system, and whether IIS-permissive SOs can be predicted from pre-onset brain states, remain unclear. Methods: We analyzed simultaneous scalp EEG and stereo-EEG (SEEG) recordings from 6...

bioRxiv 7d ago

You could get some of the benefits of sleep without having to nod off

It may one day be possible to reap some of the benefits of sleep without ever closing our eyes. Stimulating specific brain activity in awake mice led to some of the same effects as deep sleep, including a boost in memory. “It should be possible, at least in theory and to some extent, to replicate these results in our species,” says Vladyslav Vyazovskiy at the University of Oxford, who wasn’t involved in the research.

New Scientist 2d ago