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Memory decline after menopause linked to loss of estrogen production in brain

A largely overlooked space between cells in women’s brains may hold the key to understanding memory loss tied to estrogen decline after menopause, reports a new preclinical Northwestern Medicine study. Nearly two-thirds of Americans with Alzheimer’s disease (AD) are women, but the reasons why women are more vulnerable are still not fully understood. Scientists have long theorized that the loss of estrogen after menopause may reduce the brain’s natural protection against memory loss and...

Hacker News 11d ago

Novel synthetic biomolecule degrades disease-related proteins

Novel synthetic biomolecule degrades disease-related proteins Lisa Lock Scientific Editor Robert Egan Associate Editor Northwestern Medicine scientists have developed a novel synthetic biomolecular condensate that can degrade intracellular disease-causing proteins, providing a framework for new therapeutic approaches for a wide range of diseases, as detailed in a recent study published in Nature Communications. Shana Kelley, Ph.D., the Neena B. Schwartz Professor of Chemistry, Biomedical...

Phys.org 5d ago

Overlooked DNA structures help organize the genome

Overlooked DNA structures help organize the genome Lisa Lock Scientific Editor Robert Egan Associate Editor Northwestern Medicine scientists have discovered that little-studied DNA structures play a central role in organizing the human genome and controlling gene activity, according to a new study published in the Proceedings of the National Academy of Sciences. The study revealed that G-quadruplexes (G4s)—four-stranded DNA structures—directly interact with a key genome-organizing protein...

Phys.org 5d ago

Some drugs 'fail' because of unrealistic testing conditions, scientists discover

Some drugs 'fail' because of unrealistic testing conditions, scientists discover Sadie Harley Scientific Editor Robert Egan Associate Editor A drug once dismissed as ineffective suddenly worked—when scientists tested it under more realistic conditions that mimic the human body. In this surprising new discovery, Northwestern University scientists uncovered a hidden rule of drug behavior. A medicine's effectiveness can change dramatically depending on the conditions inside our cells.

Phys.org 1d ago

Should you take nutrition advice from a chatbot? Experts urge caution

Should you take nutrition advice from a chatbot? Experts urge caution Readers share their experiences asking chatbots for help with meal planning. It went well… until it didn’t.

Channel News Asia 3d ago

Flu drugs might fight cognitive decline seen in HIV, early study hints

Flu drugs might fight cognitive decline seen in HIV, early study hints A very early study suggests flu antivirals might help reverse certain signs of accelerated aging in people with HIV. But more research is needed to confirm these effects. Flu drugs may help ward off the low-grade inflammation and related cognitive decline that can come with HIV infection, an early study suggests.

Live Science 5d ago

Scientists ejected from diabetes conference for distributing journal reprints

Five leading scientists were ousted from the annual meeting of the American Diabetes Association (ADA) in New Orleans on Friday. Their crime: handing out copies of an editorial, published in the journal Diabetes Care on April 29, sharply criticizing the Trump administration’s ongoing attacks on scientific research. Those ousted were Steven Kahn, professor of medicine at the University of Washington and editor-in-chief of Diabetes Care, who co-authored the published editorial; former ADA...

Hacker News 3d ago

Scientists ejected from diabetes conference for distributing journal reprints

Five leading scientists were ousted from the annual meeting of the American Diabetes Association (ADA) in New Orleans on Friday. Their crime: handing out copies of an editorial, published in the journal Diabetes Care on April 29, sharply criticizing the Trump administration's ongoing attacks on scientific research. Those ousted were Steven Kahn, professor of medicine at the University of Washington and editor-in-chief of Diabetes Care, who co-authored the published editorial; former ADA...

Ars Technica Science 3d ago

Scientists ejected from diabetes conference for distributing journal reprints

Five leading scientists were ousted from the annual meeting of the American Diabetes Association (ADA) in New Orleans on Friday. Their crime: handing out copies of an editorial, published in the journal Diabetes Care on April 29, sharply criticizing the Trump administration's ongoing attacks on scientific research. Those ousted were Steven Kahn, professor of medicine at the University of Washington and editor-in-chief of Diabetes Care, who co-authored the published editorial; former ADA...

Ars Technica 3d ago

Cancer survivors may see surprising benefits from one specific exercise, study says

For many, surviving cancer comes with an automatic new lease on life but other survivors continue to experience physical and emotional challenges long after treatment ends. Yoga may significantly reduce the insomnia, fatigue and mood disturbances many survivors endure after remission, a recent clinical trial found. Mood disturbance and insomnia are "two of the most pervasive and troubling side effects experienced by cancer survivors for years after completing adjuvant treatments," the...

Fox News 11d ago