Periodontitis
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Related Articles from SNS
Biomaterial made from jackfruit latex is a promising treatment for periodontitis
Biomaterial made from jackfruit latex is a promising treatment for periodontitis Gaby Clark Scientific Editor Robert Egan Associate Editor Researchers from the Faculty of Medical and Health Sciences (FCMS) at the Pontifical Catholic University of São Paulo (PUC-SP) in Sorocaba, in the interior of the state of São Paulo, Brazil, have developed a biomaterial containing jackfruit latex, pomegranate peel extract, and simvastatin (a statin-based medication) that shows promising efficacy in...
First Standard Quantification of Ultrasound Attenuation in Healthy Periodontal Soft Tissues In Vivo
Announce Type: replace Abstract: This study presents the first quantifications of ultrasound attenuation in oral soft tissues using validated standard techniques and serves as foundational step in advancing quantitative ultrasound (QUS) imaging in dentistry. Current standards of care in clinics for diagnosing periodontal diseases such as inflammation are limited by subjectivity, qualitive assessment, and late-stage indication. As a result, the application of ultrasonography is emerging as a...
Nuclear confinement from matrix stiffness drives epigenomic reprogramming of gingival fibroblasts
Periodontal disease is characterized by progressive degradation of the gingival extracellular matrix and loss of the physical confinement it imposes on resident stromal cells. In human periodontal tissue, ECM collagen integrity is inversely correlated with facultative nuclear histone acetylation in stromal cells. We hypothesized that matrix stiffness directly coordinates an epigenomic shift in stromal cells.
Neutrophil-Derived Oncostatin M Contributes to Endothelial Cell Dysfunction During Treponema denticola interaction
Periodontitis (PD) is a common chronic inflammatory condition and a risk factor for cardiovascular diseases (CVD), yet underlying linking mechanisms remain unclear. The cytokine Oncostain M (OSM) is elevated in both PD and CVD and has emerged as a potential mediator linking oral inflammation to vascular dysfunction. Neutrophils represent a prominent source of OSM during PD and OSM production is elevated by the periodontal pathobiont Treponema denticola (Td).
Salivary microRNA Profiling of Long COVID Subjects Reveals Host-Encoded Regulators of Inflammation and Viral Persistence
Periodontal disease (PD) and SARS-CoV-2 infection converge upon shared immunoinflammatory axes, yet the molecular mechanisms underpinning their interplay remain insufficiently characterized. Herein, we delineate a comprehensive salivary microRNA (miRNA) repertoire from convalescent individuals with prior SARS-CoV-2 infection sampled 3-6 months post-diagnosis who fulfilled criteria for post-acute sequelae of COVID-19, yielding novel insights into the post-viral oral milieu. Salivary miRNA...
50 best oral care products, tested and reviewed
For some, oral care is like making dinner: Most people aren’t thrilled by the idea of it but you have to do it every day. You can order takeout when you’re out of meal ideas, but you can’t phone in brushing your teeth.