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Penalty-free quantum optimization applied to lattice protein folding

Announce Type: cross Abstract: Identifying minimum-energy structures of lattice proteins is a challenging discrete optimization problem. Quantum approaches such as analog quantum annealing and the gate-based quantum approximate optimization algorithm (QAOA) can address this problem after mapping it to a binary representation, which typically involves introducing penalty terms to enforce valid chain configurations. However, in this and many related problems, the use of quadratic penalty terms...

arXiv Physics 8d ago

Penalty-free quantum optimization applied to lattice protein folding

arXiv:2606.02104v2 Announce Type: replace-cross Abstract: Identifying minimum-energy structures of lattice proteins is a challenging discrete optimization problem. Quantum approaches such as analog quantum annealing and the gate-based quantum approximate optimization algorithm (QAOA) can address this problem after mapping it to a binary representation, which typically involves introducing penalty terms to enforce valid chain configurations.

arXiv Physics 7d ago

Benchmarking Quantum Algorithmic Resilience for CVaR Portfolio Optimization: The Expressibility-Coherence Trade-off

Announce Type: cross Abstract: Quantum combinatorial optimization offers theoretical advantages for complex financial modeling, but physical implementation on Noisy Intermediate Scale Quantum (NISQ) devices is severely constrained by hardware topology. This study presents a hardware benchmarking analysis between a Hardware Efficient Variational Quantum Neural Network (HE-VQNN) and the Warm Start Quantum Approximate Optimization Algorithm (WS-QAOA) for a hybrid Mean Variance and Conditional...

arXiv CS 1d ago

Mutually Unbiased Bases for Variational Quantum Initialization: Basis-Union Optimality and Adaptive Family Search

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arXiv CS 9d ago

Coordinated optimization of departure sequencing and section-track allocation in railway short-term concentrated departure scenarios based on qubo and hybrid quantum algorithms

arXiv:2606.06543v1 Announce Type: cross Abstract: This study examines the coordinated optimization of departure sequencing and section-track allocation in railway short-term concentrated departure scenarios. A quadratic unconstrained binary optimization (QUBO) model is formulated to represent departure-position assignment and section-track selection within a unified binary framework. Because the quality of a dispatching scheme depends on time-dependent operational interactions that cannot be...

arXiv CS 2d ago