Rifampicin

Researchers discover how to turn one germ's drug resistance into an Achilles' heel

Researchers discover how to turn one germ's drug resistance into an Achilles' heel Lisa Lock Scientific Editor Andrew Zinin Lead Editor Decades of reliance on the antibiotic rifampicin have fueled the rise of drug-resistant Mycobacterium tuberculosis (Mtb). But as the bacterium mutates to protect itself from the drug, it also creates new weak points that other therapies could exploit. Now, a new study published in Nature Microbiology shows that the most common rifampicin-resistance mutation...