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Related Articles from SNS
A first-in-class pulsatile FXR agonist for bile-acid-related liver diseases
Abstract Nuclear receptors are central regulators of metabolism1, yet therapeutic strategies that enforce continuous receptor activation frequently lead to reduced efficacy and unacceptable toxicity. Here we report a first-principles drug design strategy that aligns pharmacokinetics with physiological signalling cycles. We developed linafexor, a potent non-bile-acid agonist of the farnesoid X receptor (FXR)2; it is engineered for rapid systemic clearance, which enables pulsatile receptor...
SpaceVLN: A Zero-Shot Vision-and-Language Navigation Agent with Online Spatial Cognitive Memory and Reasoning
arXiv:2606.08992v1 Announce Type: new Abstract: Vision-and-Language Navigation in continuous environments requires agents to understand the spatial structure of previously unseen environments in order to follow language instructions. Although foundation models have opened a promising path toward zero-shot navigation without task-specific policy training, many navigators still rely on local visual cues and linear history-based reasoning, overlooking the spatial nature of navigation across...
Qwen-VLA: Unifying Vision-Language-Action Modeling across Tasks, Environments, and Robot Embodiments
arXiv:2605.30280v2 Announce Type: replace Abstract: Embodied intelligence is often studied through specialized models for individual tasks such as manipulation or navigation, resulting in fragmented capabilities and limited generalization across tasks, environments, and robot embodiments. In this work, we study whether heterogeneous embodied decision-making problems can be unified within a single vision-language-action model. We present Qwen-VLA, a unified embodied foundation model that...