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A differentiable machine learning small-angle X-ray scattering analysis framework for structure elucidation of lipid nanoparticles

Announce Type: cross Abstract: Lipid nanoparticles (LNPs) are efficient delivery systems for negatively charged nucleic acids. Their multi-component architecture yields a core-shell structure. Small-angle X-ray scattering (SAXS) is an important characterization technique for LNPs, but recovering internal structure and size distribution from SAXS is an inverse problem with non-unique solutions.

arXiv CS 5d ago

A differentiable machine learning small-angle X-ray scattering analysis framework for structure elucidation of lipid nanoparticles

Announce Type: new Abstract: Lipid nanoparticles (LNPs) are efficient delivery systems for negatively charged nucleic acids. Their multi-component architecture yields a core-shell structure. Small-angle X-ray scattering (SAXS) is an important characterization technique for LNPs, but recovering internal structure and size distribution from SAXS is an inverse problem with non-unique solutions.

arXiv Physics 5d ago

Magic, mastery and magisterial power: 10 of Sonny Rollins’ greatest recordings

After his death aged 95, we look back at a remarkable catalogue of work that stretches from vivacious mid-50s sets to his evocative performance after 9/11• News: Sonny Rollins, colossus of jazz saxophone, dies aged 95A 30-year-old Sonny Rollins had already made his unique mark with Miles Davis and Thelonious Monk by the time this 1956 session was cut, just a year after bebop sax revolutionary Charlie Parker’s death – but hooking up with his contemporary and admirer John Coltrane happened by...

The Guardian Culture 15d ago

From Cape Fear to Zoh Amba: the week in rave reviews

Javier Bardem is at his menacing best in a wild remake of the psychological thriller, and the jazz sax maven surprises with raw country rock spirituality. Here’s the pick of the week’s culture, taken from the Guardian’s best-rated reviews Continue reading...

The Guardian Culture 4d ago

From Cape Fear to Zoh Amba: the week in rave reviews

Javier Bardem is at his menacing best in a wild remake of the psychological thriller, and the jazz sax maven surprises with raw country rock spirituality. Here’s the pick of the week’s culture, taken from the Guardian’s best-rated reviews Continue reading...

The Guardian UK 4d ago

Correlative X-ray imaging and fluorescence microscopy

Imaging the structural organization inside cells in their native state is essential for understanding how the arrangement and interactions among molecular components give rise to biological function. Fluorescence microscopy is one of the pivotal techniques that provides molecular specificity for imaging in real space, however, the technique is limited to labeled components. X-rays, on the contrary, are sensitive to electron density contrast and therefore to label-free samples, and probe...

bioRxiv 6d ago

CardioMorphNet: Cardiac Motion Prediction Using a Shape-Guided Bayesian Recurrent Deep Network

Announce Type: replace Abstract: Accurate cardiac motion estimation from cine cardiac magnetic resonance (CMR) images is vital for assessing cardiac function and detecting its abnormalities. Existing methods often struggle to accurately capture heart motion because they rely on intensity-based image registration similarity losses that may overlook cardiac anatomical regions. To address this, we propose CardioMorphNet, a recurrent Bayesian deep learning framework for 3D cardiac shape-guided...

arXiv CS 1d ago

TSseek: Regular Expression-Based Similarity Search for Distributed Time Series Datasets

arXiv:2606.09824v1 Announce Type: new Abstract: Similarity search is a fundamental operation in time series analysis. Most existing techniques, however, require users to supply a precise sequence of values (typically an entire time series object) as the query input. This rigid requirement limits real-world applications, where users instead want to express patterns, trends, or value ranges.

arXiv CS 1d ago

Magic, mastery and magisterial power: 10 of Sonny Rollins’ greatest recordings

Jazz saxophone legend Sonny Rollins has passed away at the age of 95. His extensive catalogue of work is being celebrated, spanning from energetic mid-50s performances to later evocative recordings. The article highlights his early inventive period, noting his work with Miles Davis and John Coltrane.

The Guardian UK 15d ago