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Auditable recovery of single-cell RNA-seq zeros with SPARE

In Single-cell RNA-seq, observed zeroes are the mix between biological absence and technical limitations. However, current evaluation metrics fail to distinguish between these two states, focusing on reconstruction accuracy rather than the biological validity of edits. We introduce SPARE, a partition-aware framework that audits the imputation process by cataloging observed zeros as edited, unchanged, or marker-vetoed prior to sequence reconstruction.

bioRxiv 5d ago

I'm Ohio's state auditor — Medicaid fraud is not just a Washington problem

When I testify on Capitol Hill, I’ll be addressing the fact that my home state of Ohio is not immune to the sophisticated fraud and abuse plaguing Medicaid and other government programs nationally. Wherever there are big government programs backed by big government spending, there will be people who find ways to exploit loopholes and lax controls to fill their own pocketbooks. Left unaddressed by the state bureaucracies, these weaknesses invite outside manipulation and erode public trust.

Fox News 7d ago

A Held-Out Transition-Pair Falsifier for Long-Horizon Non-Abelian State Tracking

Announce Type: new Abstract: State tracking exposes a sharp limitation of sequence models: the relevant signal is often not a summary of observed tokens, but an ordered latent state that evolves through non-commutative transformations. We introduce a held-out transition-pair falsifier for finite non-Abelian group tracking. The protocol forbids selected ordered generator pairs during training and requires the same local patterns during evaluation, blocking one direct local-transition...

arXiv CS 2d ago

Listen up, England. The Health Secretary is going to be data controller for everyone's Single Patient Record

Health secretary James Murray has said that he will become a data controller of all National Health Service records in England shared through the government’s planned single patient record (SPR). Murray, who is formally the secretary of state for health, told the House of Commons on 1 June that GP surgeries, NHS trusts and other care providers will continue to manage and take responsibility for their own records, but added: “Where that information is then shared through the single patient...

The Register 7d ago

Show HN: Nucleus – A security-hardened, Nix-native container runtime

Extremely lightweight, security-hardened, declarative container runtime for agents and production services Nucleus is a minimalist container runtime for Linux. It provides isolated execution environments using Linux kernel primitives without the overhead of traditional container runtimes. For production services, it is designed around a fully declarative model: Nix builds the root filesystem, the NixOS module declares the service, and Nucleus mounts a pinned, reproducible closure at runtime.

Hacker News 22h ago

Pepper: High-bandwidth and Scalable Anonymous Broadcast with Cryptographic Privacy

arXiv:2606.04411v1 Announce Type: new Abstract: We present Pepper, a high-bandwidth anonymous broadcast protocol that provides cryptographic sender anonymity against global adversaries. Pepper builds on a two-server DC-net architecture but introduces three key innovations: a self-contained anonymous registration subprotocol using verifiable distributed point functions, support for batch messaging via distributed multi-point functions, and a lightweight access control mechanism based on...

arXiv CS 6d ago

Lawmakers sound the alarm on Trump’s ‘most dangerous’ Cabinet pick

Lawmakers sound the alarm on Trump’s ‘most dangerous’ Cabinet pick Bill Pulte’s temporary role as intelligence director is just long enough to disrupt midterm elections, Democrats fear - Bookmark - CommentsGo to comments Top Democrats overseeing national intelligence fear President Donald Trump’s controversial pick for Director of National Intelligence could sow chaos in national security matters — especially ahead of the midterm elections. Lawmakers from both sides of the aisle have...

The Independent World 2d ago

Home Office ditches legacy asylum database, keeps the spreadsheets

The UK's long-running asylum IT overhaul may finally have put the 25-year-old Case Information Database (CID) out to pasture, but Parliament says that officials are still relying on spreadsheets and disconnected systems to keep track of asylum cases. A new report from the Public Accounts Committee (PAC) found asylum data remains scattered across multiple systems, making it difficult for officials to track cases, spot emerging backlogs, or understand where pressure is building across the...

The Register 3d ago

ZERO-APT: A Closed-Loop Adversarial Framework for LLM-Driven Automated Penetration Testing under Intelligent Defense

arXiv:2606.05567v1 Announce Type: new Abstract: LLM-driven automated penetration testing agents are typically evaluated against static targets that neither detect nor respond to attacks, so their behavior under intelligent defense remains untested. The causal consistency of multi-step attack chains likewise hinges on unstable LLM reasoning, and agent decisions remain opaque to human analysts. These three shortcomings, in realism, consistency, and auditability, are usually patched in isolation.

arXiv CS 5d ago

DuMate-DeepResearch: An Auditable Multi-Agent System with Recursive Search and Rubric-Grounded Reasoning

arXiv:2606.07299v1 Announce Type: new Abstract: Deep Research (DR) has emerged as a new agentic paradigm to tackle complex, open-ended research tasks, demanding systems that can iteratively frame problems, acquire evidence, verify sources, and synthesize long-form reports. In practice, however, current DR systems are constrained by four interrelated limitations: long-horizon planning over an underspecified scope, the bottleneck of decomposing and scheduling such tasks within a single agent,...

arXiv CS 2d ago