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Related Articles from SNS
Chronic Stress Exacerbates Long-term Microvascular Network Dysfunction Following Brain Trauma
Background: Preexisting factors are among the strongest predictors of recovery following traumatic brain injury (TBI), with chronic stress closely associated with permanent disability and worse long-term outcomes. While chronic cerebrovascular dysfunction is linked to these poor trajectories, as impaired blood flow regulation drives secondary disease progression, the mechanisms regulating this vascular failure remain incompletely understood. Crucially, how premorbid chronic stress and TBI...
Combinatorial screening of nanoparticles for nose-to-brain RNA delivery to modulate neuroinflammation after traumatic brain injury
Traumatic brain injury (TBI)-induced neuroinflammation can evolve over weeks or months,contributing to ongoing secondary damage and worsening neurological recovery. RNA-based therapeutics hold great potential to regulate inflammatory signaling, but delivery to the brain remains challenging because of the blood brain barrier. Intranasal administration offers a direct non-invasive route for brain access but is often limited by low delivery efficiency.
Heading a soccer ball just once is enough to raise levels of proteins associated with brain damage
Heading a soccer ball just once is enough to raise levels of proteins associated with brain damage Amateur male soccer players had greater changes in certain blood markers associated with neural damage the harder and more frequently they headed balls. Heading a soccer ball just once is enough to temporarily release proteins into the blood that are associated with damage to brain cells, a new study suggests. For two of the six proteins tracked, their levels rose higher the more frequently and...
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