TME
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Iron-deficiency in the tumor microenvironment reprograms tumor-immune interactions in a sex biased manner
Background: Glioblastoma (GBM) is a sex-biased disease characterized by higher incidence and poorer survival in males. These sex differences are primarily driven by metabolic and immune signatures, with iron metabolism playing a major role. While iron is essential for tumor cell proliferation, it is also critical for T cell recruitment and function within the tumor microenvironment (TME).
HOPE: Interpretable Histology Analysis with Spatial Omics-Derived Signatures for Precision Oncology
Hematoxylin and eosin (H&E) stained images are fundamental clinical tools for disease assessment. However, even with advanced computational models, their prognostic capabilities remain limited. Spatial omics characterizes tumor microenvironments (TME) in detail yet remains clinically inaccessible due to cost and complexity.
The Sharp Phase Transition of Tyler's M-Estimator for Robust Subspace Recovery
arXiv:2606.06782v1 Announce Type: new Abstract: Robust Subspace Recovery (RSR) aims to identify an underlying d-dimensional subspace from a dataset heavily corrupted by outliers. Complexity-theoretic results establish a threshold for the problem's computational hardness based on the dimension-scaled signal-to-noise ratio (DS-SNR): the problem is SSE-hard when the DS-SNR is strictly less than 1, and solvable via practical algorithms when it is greater than 1 under general position...
FP8 is All You Need (Part 1): Debunking Hardware FP64 as the HPC Holy Grail
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