Tang Wei
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Chinese man, 19, lives under bridge with pet dog, works long hours to save for tuition
Chinese man, 19, lives under bridge with pet dog, works long hours to save for tuition ‘Hardship’ suffering teenager from poor rural background attracts donations from fellow city dwellers thanks to his ‘kindness’ Residents of a city in central China have come to the aid of a poor 19-year-old student who works more than 10 hours a day as a food delivery rider to earn money to cover his tuition fees. Tang Wei, from Xinhuang county in Hunan province, was admitted by a technical college in...
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New solar desalination breakthrough makes fresh water without toxic brine
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Structural basis for chaperone-guided assembly of RNA-induced silencing complex
Abstract The RNA-induced silencing complex (RISC), comprising an Argonaute (AGO) protein and a small RNA, is the central effector in RNA silencing. Small RNAs are loaded onto AGO as bulky duplexes in an HSP70- and HSP90-dependent process1,2,3, but the molecular mechanism remains poorly understood. Here we identify the human AGO–HSP90–p23 complex, which captures AGO in an RNA-free state, termed the AGO maturation complex (AMC).