Thalamocortical Coupling
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Related Articles from SNS
Thalamic Nuclei Differentially Coordinate Propagation of Cortical Slow Oscillations
Sleep slow oscillations (SOs) vary in the spatial extent of their cortical propagation, ranging from widespread Global events to spatially restricted Frontal events. These distinctions could have functional consequences for memory consolidation. It remains unknown whether individual thalamic nuclei are differentially engaged across SO propagation types, and whether thalamic activity before SO onset predicts subsequent propagation.
Slow Oscillations Gate Interictal Spikes Across the Human Thalamocortical-Epileptogenic Network
Background: Slow oscillations (SOs; 0.5-1.5 Hz), a hallmark of non-rapid eye movement (NREM) sleep, are associated with a marked amplification of interictal epileptiform spike (IIS) activity in focal epilepsy. However, the network-level organization of this effect across the thalamocortical-epileptogenic system, and whether IIS-permissive SOs can be predicted from pre-onset brain states, remain unclear. Methods: We analyzed simultaneous scalp EEG and stereo-EEG (SEEG) recordings from 6...