UK Dementia Research Institute
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A prognostic human brain network for diffuse midline glioma
Abstract Diffuse midline gliomas (DMGs) are near-universally lethal tumours of the childhood central nervous system1,2. In animal models, DMGs form brain-wide integrated networks through neuron-to-glioma synapses3,4,5,6 and glioma-to-glioma gap junctional coupling3. This extensive connectivity robustly promotes the growth and invasion of DMG3,4,5,6,7,8,9 and other glial malignancies10,11,12 through paracrine mechanisms and direct neuron-to-glioma synapses.
A blood test could flag Alzheimer’s risk early. But how reliable is it?
Scientists have developed a blood test that could spot signals of Alzheimer's disease at a much younger age. A simple blood test may soon help identify people at higher risk of Alzheimer’s disease years before they develop symptoms, according to a new study. Researchers at the University of California, San Francisco (UCSF) in the United States, found that certain Alzheimer’s-related proteins in the blood were linked to small differences in thinking and memory among middle-aged adults who did...