UT Southwestern Medical Center
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Ebola outbreak in DR Congo could top 20,000 cases in worst case, CDC says
The Ebola outbreak in the Democratic Republic of the Congo and Uganda could lead to more than 20,000 cases and over 2,000 deaths in a worst-case scenario, according to a report published Friday by the Centers for Disease Control and Prevention. That scenario — modeled using data through May 24, when about 50 deaths had been reported — assumes that only 20% of Ebola patients isolate and that access to vaccines and treatments is limited, the agency said. The outbreak is caused by a rare type...
Mitochondria directly interact with the nuclear pore complex
Abstract Mitochondria regulate cellular processes through direct and indirect interactions with other organelles. A well-studied example has been contact with the endoplasmic reticulum at mitochondrial-associated endoplasmic reticulum membranes1, which control pathways including redox and calcium homeostasis2,3. Recent studies have also reported direct mitochondria–nuclear membrane contacts in cancer cells and yeast that promote pro-survival signalling4,5.