Université de Montréal
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Embryos shape their limbs: a key discovery of "genetic brakes"
Canadian scientists have made a significant advance in understanding the mechanisms that enable embryos to properly form their limbs, thanks to new research led by Université de Montréal medical professor Marie Kmita at the Montreal Clinical Research Institute (IRCM). In findings published in the journal PNAS, Kmita and her team highlight the crucial role of certain molecular systems that act as true “genetic brakes,” ensuring that development proceeds correctly. At the very beginning of...
'Genetic brakes' reveal how embryos shape their limbs
Canadian scientists have made a significant advance in understanding the mechanisms that enable embryos to properly form their limbs, thanks to new research led by Université de Montréal medical professor Marie Kmita at the Montreal Clinical Research Institute (IRCM). In findings published in the Proceedings of the National Academy of Sciences, Kmita and her team highlight the crucial role of certain molecular systems that act as true "genetic brakes," ensuring that development proceeds...
The path to teen radicalization isn't as straight as people think
The path to teen radicalization isn't as straight as people think Gaby Clark Scientific Editor Andrew Zinin Lead Editor Amid growing public concern about the radicalization of young people, there is a widespread misconception that radicalization logically and inevitably progresses to violence. It is often assumed that once exposed to certain ideas, teenagers latch on to them and gradually move on to increasingly extreme views. However, a new study led by Diana Miconi, a professor in the...
The secret reason some cancer treatments stop working
The secret reason some cancer treatments stop working - Date: - June 9, 2026 - Source: - University of Montreal - Summary: - Scientists have uncovered a hidden immune system "brake" that may help cancers avoid being destroyed. The molecule, called SLAMF6, weakens the body's cancer-fighting T cells and can leave them exhausted over time. Researchers developed antibodies that block this brake, allowing immune cells to stay stronger and attack tumors more effectively in mice.