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Intermittent fasting triggers surprising changes in the brain

Intermittent fasting triggers surprising changes in the brain An intermittent fasting-style diet helped obese adults lose weight while triggering coordinated changes in both their gut bacteria and brain activity. - Date: - May 31, 2026 - Source: - Frontiers - Summary: - Losing weight may involve rewiring the gut and the brain at the same time. In a study of obese adults, an intermittent fasting-style diet led to significant weight loss, healthier metabolic markers, and notable shifts in gut...

Science Daily 10d ago

Nvidia Cosmos 3

Physical AI systems must understand the real world before they can act within it. Robots, autonomous vehicles, and smart spaces need to understand what’s happening in their world, predict what’s likely to happen next, and generate actions for specific environments, embodiments, and tasks. NVIDIA Cosmos 3 is a frontier foundation model for physical AI that combines physical reasoning, world generation, and action generation within a single open model.

Hacker News 9d ago

A thalamus–brainstem attractor network drives history-biased decisions

Abstract Natural environments often change gradually, making it adaptive to bias decisions on the basis of the recent past — a phenomenon known as serial dependence1,2,3. Large-scale recordings during behaviour have identified that serial dependence is a common motif for decision-making, with neural representations of past experiences found throughout the brain4,5,6,7,8,9,10,11. However, it remains unclear whether this bias arises from dedicated neural circuits with history-specific...

Nature 21h ago

Light-induced quantum friction of carbon nanotubes in water

Abstract Friction slows down moving objects at both macroscopic and microscopic scales1. At the electronic level, quantum friction describes direct transfer of momentum between a liquid and the electrons of a solid2. Owing to its microscopic nature, this phenomenon remains experimentally challenging to capture3.

Nature 21h ago

Measurement of reactor neutrino oscillation with the first JUNO data

Abstract Neutrino oscillations (see refs. 1,2 and references therein), a quantum effect manifesting at macroscopic scales, are governed by lepton flavour mixing angles and neutrino mass-squared differences3 that are fundamental parameters of particle physics, representing phenomena beyond the Standard Model. Precision measurements of these parameters are essential for testing the completeness of the three-flavour framework, determining the mass ordering of neutrinos and probing possible new...

Nature 21h ago

Doctors thought this kidney drug helped some patients. It may help millions more.

Doctors thought this kidney drug helped some patients. It may help millions more. - Date: - June 8, 2026

Science Daily 2d ago

A first-in-class pulsatile FXR agonist for bile-acid-related liver diseases

Abstract Nuclear receptors are central regulators of metabolism1, yet therapeutic strategies that enforce continuous receptor activation frequently lead to reduced efficacy and unacceptable toxicity. Here we report a first-principles drug design strategy that aligns pharmacokinetics with physiological signalling cycles. We developed linafexor, a potent non-bile-acid agonist of the farnesoid X receptor (FXR)2; it is engineered for rapid systemic clearance, which enables pulsatile receptor...

Nature 21h ago

SIRT7 regulates dosage compensation and safeguards the female X chromosome

Abstract Sirtuins are deacetylases implicated in stress responses and longevity in mammals1,2. Although their differential impact on disease for the two sexes has been noted3,4,5,6,7, the underlying reasons are unclear. Here, using Sirt7 as a model in mice, we examine the mechanisms leading to sex differences and find that Sirt7−/− female mice have decreased fitness throughout their lifespan.

Nature 21h ago

Scientists mapped every neural connection in a fruit fly and found a surprise

Scientists mapped every neural connection in a fruit fly and found a surprise Scientists have completed the first full brain-to-body wiring map of a fruit fly, revealing that behavior may be driven more by local neural teamwork than by a central brain command center. - Date: - June 10, 2026 - Source: - Harvard Medical School - Summary: - A groundbreaking new connectome maps every neural connection in an adult fruit fly’s central nervous system, creating an unprecedented view of how the brain...

Science Daily 11h ago

Human-Like Neural Nets by Catapulting

Human-like Neural Nets by Catapulting Speculative proposal to create artificial neural nets with human-like performance by high-learning-rate/regularization training of overparameterized NNs to trigger catapulting/grokking. Over-parameterization as a route to true generalization would resolve many outstanding mysteries of artificial versus natural intelligence. There are many mysteries about deep learning and human intelligence, but we could describe the biggest anomaly this way: why are...

Hacker News 3d ago